2'- O- Monobutyrylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-MB-cGMP )

Metabolically activatable PKG agonist
Cat. No.: M 006   CAS No.: [58329-72-9]   Bulk available
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C14H17N5O8P.Na; MW 437.3; λmax 252 nm; ε 13500; sodium salt; purity > 97% HPLC. For other salt forms or metabolites please inquire. 2'-O-MB-cGMP is a lipophilic precursor of cyclic GMP. During metabolic activation by esterases cGMP and butyrate are released. Caution: Butyrate was shown to have distinct biological effects. Significantly more lipophilic and membrane-permeant compared to cGMP. Detailed technical information available. Reference: Hebert et al., J. Biol. Chem., 273, 5557 - 5565 (1998).

 



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