Basket (0 Items) - Amount: 0.00$2'- O- Monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-2'-O-MB-cAMPS )
Metabolically activatable form of the PDE-resistant PKA agonist Sp-cAMPS
Cat. No.: M 005 CAS No.: [152218-23-0]
C14H17N5O6PS•Na; MW 437.4; λmax 258 nm; ε 15000; sodium salt; purity > 97%. For other salt forms please inquire. Sp-2'-O-MB-cAMPS is a lipophilic precursor of Sp-cAMPS (Cat. No. A 003) a PDE-resistant activator of protein kinase A. During metabolic activation by esterases Sp-cAMPS and butyrate are released. Caution: Butyrate was shown to have distinct biological effects! Significantly more lipophilic and membrane-permeant compared to Sp-cAMPS. Detailed technical information available. Reference: Hügl et al., J. Biol. Chem., 273, 17771 - 17779 (1998).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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