C₁₀H₁₆N₅O₁₃P₃S; MW 539.3 (free acid); λ_max 252 nm; ε 14300; sodium salt, purity > 95% HPLC. For other salt forms or higher purity please inquire. Useful for modulation of GTP-responsive receptors and determination of their stereospecificity (Eckstein, Ann. Rev. Biochem., 54, 367 - 402 (1985)). Increased metabolic stability compared to GTP. Accepted by RNA polymerase for incorporation of phosphorothioate into RNA, by guanylate cyclase for cyclisation to Sp-cGMPS and by tubulin (Xu et al., Biochim. Biophys. Acta, 1383, 111 - 122 (1998)). Detailed technical information available.

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6