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pdAp

2'- Deoxyadenosine- 3', 5'- O- bisphosphate ( pdAp ), sodium salt
Modulator of purinergic receptors
Cat. No.: D 092
    
CAS No.: [16174-58-6]
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Product Name Price (net) Qty
Cat. No.: D 092-05
Unit: 5 µmol / ~2.1 mg
$372.00
For other salt forms or analogues please inquire. Accepted by T4 RNA ligase to build oligodeoxyribonucleotides (Hinton et al., Biochemistry, 17, 5091 - 5097 (1978)) and modulator of purinergic receptors (Camaioni et al., J. Med. Chem., 41, 183 - 190 (1998)). Detailed technical information available.
Cat. No. D 092
CAS number [16174-58-6]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₅N₅O₉P₂ (free acid)
Molecular weight [g/mol] 411.2 (free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
  • 1. Nandanan E., Camaioni E., Jang S.-Y., Kim Y.-C., Cristalli G., Herdewijin P., Secrist J. A., Tiwari K. N., Mohanram A., Harden T. K., Boyer J. L.Jacobson K. A., J. Med. Chem., 42, 1625 - 1638 (1999), "Structure-Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y1 Receptor Antagonists and Partial Agonist"
  • 2. Camaioni E., Boyer J. L., Mohanram A., Harden T. K.Jacobson K. A., J. Med. Chem., 41, 183 - 190 (1998), "Deoxyadenosine Bisphosphate Derivatives as Potent Antagonists at P2Y1 Receptors"
  • 3. Hinton D. M., Baez J. A.Gumport R. I., Biochemistry, 17, 5091 - 5097 (1978), "T4 RNA Ligase Joins 2'-Deoxyribonucleoside 3',5'-bisphosphates to Oligodeoxyribonucleotides"