Basket (0 Items) - Amount: 0.00$(7- Dimethylaminocoumarin-4- yl)methyl- 8- bromoadenosine- 3', 5'- cyclic monophosphate ( DMACM-caged 8-Br-cAMP )
Caged 8-Br-cAMP releasing fluorescent coumarin upon irradiation
Cat. No.: D 044
C22H22BrN6O8P x H2O; MW 627.4; λmax 393 nm; ε 16100; purity > 98%. Axial isomer, for the corresponding isomeric mixture please inquire. DMACM-caged 8-Br-cAMP is an only weakly fluorescent, caged precursor of 8-bromo cyclic AMP, which upon irradiation, releases both 8-Br-cAMP and a fluorescent coumarin analogue. High lipophilicity and membrane permeability; thus only limited solubility in aqueous systems. Detailed technical information available. For a similar approach please compare: Hagen et al., J. Photochem. Photobiol. B: Biol., 53 (1999).
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