5, 6- Dichlorobenzimidazole riboside- 3', 5'- cyclic monophosphate ( 5,6-DCl-cBIMP )
Membrane-permeant, ultra-potent PKA agonist
Cat. No.: D 011 CAS No.: [129693-10-3]
C12H10Cl2N2O6P•Na; MW 403.1; λmax 254 nm; ε 6400; sodium salt, purity > 98% HPLC. For other salt forms or metabolites please inquire. Potent and lipophilic activator of protein kinase A, type I & II. Ten times more active compared to cyclic AMP but rapidly degraded by cyclic nucleotide-dependent phosphodiesterases. Detailed technical information and references available. Reference: Dostmann et al., J. Biol. Chem., 265, 10484 - 10491 (1990).
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