N6, 2'- O- Dibutyryladenosine- 3', 5'- cyclic monophosphate ( DB-cAMP, Bucladesine ), high purity grade
C18H23N5O8P•Na; MW 491.4; λmax 273 nm; ε 17000; sodium salt, purity > 98% HPLC. Membrane-permeant activator of protein kinase A (cyclic AMP agonist). Detailed technical information including hints about potential pitfalls and selected references available. Reference: Posternak et al., Methods Enzymol., 38, 399 (1974). Caution: This analogue releases butyrate due to intracellular and extracellular esterase action. Butyrate was shown to have distinct biological effects! We offer numerous more recommendable cAMP agonists. DB-cAMP is also available in an inexpensive low purity form ( D 009 Economy Grade ).
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