C₂₁H₂₈N₅O₁₀P; MW 541.5; λ_max 273 nm; ε 17000. Purity > 97% HPLC for mixture of axial and equatorial isomer. Highly potent and membrane-permeant precursor of DB-cAMP. Releases dibutyryl cAMP after metabolic activation by esterases. Due to further degradation to the much more polar monobutyryl cAMP and cAMP the kinase activators are trapped inside the cell. Detailed technical information and references available. Reference: Schultz et al., J. Biol. Chem., 268, 6316 - 6322 (1993). Caution: This analogue releases butyrate due to intracellular and extracellular esterase action. Butyrate was shown to have distinct biological effects!

Biolog also offers Phosphate tris(acetoxymethyl)ester (PO₄-AM₃, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.