Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( cCMP-AM )
Highly membrane-permeant prodrug form of the second messenger cyclic CMP

C12H16N3O9P; MW 377.2; λmax 270 nm; ε 9000; purity > 95% HPLC for mixtures of axial and equatorial isomer. Membrane-permeant, metabolically activatable prodrug form of the potential further second messenger cyclic CMP (Cat. No. C 001). After permeation and metabolic activation by esterases the polar cCMP is released which is trapped inside the cell and subsequently metabolized quickly, resulting in a pulse-type signal. Detailed technical information available.
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
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