Basket (0 Items) - Amount: 0.00$8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-CPT-cAMP-AM )
Metabolically activatable prodrug form of 8-CPT-cAMP
Cat. No.: C 056 CAS No.: [663941-66-0]
C19H19ClN5O8PS; MW 543.9; λmax 282 nm; ε 16000; purity > 97% HPLC for mixture of axial and equatorial isomers. Membrane-permeant precursor of the PKA activator 8-CPT-cAMP (Cat. No. C 010). Metabolic activation by esterases releases the active analogue. Detailed technical information available. Reference: Kruppa et al., Bioorg. Med. Chem. Lett., 7, 945 - 948 (1997).
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
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