Basket (0 Items) - Amount: 0.00$8- (4- Chlorophenylthio)- ß- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-pCPT-PET-cGMPS )
Potent, PDE-resistant inhibitor of protein kinase G
Cat. No.: C 046 CAS No.: [pending]
C24H18ClN5O6PS2•Na; MW 626.0; λmax 276 nm; ε 40000; sodium salt, purity > 99% HPLC. Potent inhibitor of protein kinase G. Most probably retinal cGMP-gated ion channels are inhibited as well. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane-permeant compared to all other cGK inhibitors offered. Detailed technical information available on request.
Protected under patents US 5,625,056, DE 42 17679 & DE 3802865.4 issued or licensed exclusively to BIOLOG LSI
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