This website uses cookies to ensure proper functionality of the shopping cart and checkout progress. By continuing to browse the site you are agreeing to the use of cookies. Click here to learn about cookie settings.
Biomarker for analysis of chlorine stressed RNA and useful starting structure for nucleosides and nucleotides modified in position 5 of the pyrimidine nucleobase. For 5- chlorocytosine please inquire. Detailed technical information available. Reference: Badouard et al., J. Chromatogr., 827, 26 - 31 (2005). This compound is also part of the Ko-Libri compound library (K 001)
Cat. No.
C 034
CAS number
[25130-29-4]
Purity
> 98% HPLC
Storage temperature
-20°C / -4°F
Molecular formula
C₉H₁₂ClN₃O₅
Molecular weight [g/mol]
277.7
Absorption max [nm]
287
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]
7250
1. Stanley N. R., Pattison D. I.Hawkins C. L., Chem. Res. Toxicol., 23, 1293 - 1302 (2010), "Ability of Hypochlorous Acid and N-Chloramines to Chlorinate DNA and Its Constituents"
2. Badouard C., Masuda M., Nishino H., Cadet J., Favier A.Ravanat J.-L., J. Chromatogr., 827, 26 - 31 (2005), "Detection of Chlorinated DNA and RNA Nucleosides by HPLC Coupled to Tandem Mass Spectrometry as Potential Biomarkers of Inflammation"
3. Masuda M., Suzuki T., Friesen M. D., Ravanat J.-L., Cadet J., Pignatelli B., Nishino H.Oshima H., J. Biol. Chem., 276, 40486 - 40496 (2001), "Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils"