Basket (0 Items) - Amount: 0.00$8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-pCPT-cGMP-AM )
Highly membrane-permeant prodrug form of the PKG agonist 8-pCPT-cGMP
Cat. No.: C 033 CAS No.: [272445-72-4]
C19H19ClN5O9PS; MW 559.9; λmax 276 nm; ε 21500; purity > 97% HPLC for mixture of axial and equatorial isomer. Highly membrane-permeant precursor of the PKG activator 8-pCPT-cGMP (Cat. No. C 009). Metabolic activation by esterases releases the active analogue. Detailed technical information available. Reference: Schwede et al., Bioorg. Med. Chem. Lett., 10, 571 - 573 (2000).
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
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