Basket (0 Items) - Amount: 0.00$8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-pCPT-cGMPS )
Membrane-permeant and PDE-resistant PKG agonist
Cat. No.: C 014 CAS No.: [160385-87-5]
C16H14ClN5O6PS2•Na; MW 525.9; λmax 276 nm; ε 21500; sodium salt; purity > 99% HPLC, fluorescent impurities removed. For other salt forms please inquire. Activator of protein kinase G type I α and type II. Caution: Protein kinase A type II is activated as well. Excellent cell membrane permeability and phosphodiesterase stability. Detailed technical information and updated reference list available on request. References: Butt et al., Eur. J. Pharmacol., 269, 265 - 268 (1994), Gamm et al., J. Biol. Chem., 270, 27380 - 27388 (1996).
Protected under patents US 5,625,056, DE 42 17679 & DE 3802865.4 issued or licensed exclusively to BIOLOG LSI
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