8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-CPT-cAMPS )

Lipophilic, site-selective and PDE-resistant activator of protein kinase A.
Cat. No.: C 012   CAS No.: [129693-13-6]   
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C16H14ClN5O5PS2•Na; MW 509.8; λmax 282 nm; ε 16000; sodium salt; purity > 99% HPLC. Specially purified quality, fluorescent impurities removed. Lipophilic site-selective activator of protein kinase A (cyclic AMP agonist). Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Highly membrane-permeant. Detailed technical information and updated reference list available on request. Reference: Dostmann et al., J. Biol. Chem., 265, 10484 - 10491 (1990).

Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI

 



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