8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-Br-2'-O-Me-cAMP-AM )
Metabolically activatable Epac agonist
Cat. No.: B 028 CAS No.: [pending]

C14H17BrN5O8P; MW 494.2; λmax 264 nm; ε 17000; purity > 97% HPLC for mixture of isomers. Extremely membrane-permeant precursor of the specific Epac agonist 8-Br-2'-O-Me-cAMP (Cat. No. B 022). After permeation and metabolic activation by esterases the active compound is released. Detailed technical information available. Reference: Börner et al., Nature Protocols, 6, 427 - 438 (2011).
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
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