[6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( BCMCM-caged 8-Br-cGMP )

Caged cyclic GMP, releasing a fluorescent coumarin upon un-caging
Cat. No.: B 019   CAS No.: [370091-68-2]   
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C24H21BrN5O15P x 3 H2O; MW 784.4; λmax 346 nm; ε 11200; purity > 98% HPLC. Equatorial isomer, for the corresponding axial isomer or isomeric mixtures please inquire. BCMCM-caged 8-Br-cGMP is an only weakly fluorescent, caged precursor of 8-bromo cyclic cGMP, which upon irradiation, releases both 8-Br-cGMP and a fluorescent coumarin analogue. Excellent solubility in water or buffers. Detailed technical information available. For reference please compare: Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).

Protected by patent DE 100 21 256.5 and foreign equivalents 

 



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