[6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- 8- bromoadenosine- 3', 5'- cyclic monophosphate ( BCMCM-caged 8-Br-cAMP )
C24H21BrN5O14P x 2.5 H2O; MW 759.4; λmax 346 nm; ε 10300; purity > 98% HPLC. Equatorial isomer, for the corresponding isomeric mixture please inquire. BCMCM-caged 8-Br-cAMP is an only weakly fluorescent, caged precursor of 8-bromo cyclic cAMP, which upon irradiation, releases both 8-Br-cAMP and a fluorescent coumarin analogue. Excellent solubility in water or buffers. Detailed technical information available. Reference: Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).
Protected by patent DE 100 21 256.5 and foreign equivalents
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