Basket (0 Items) - Amount: 0.00$[6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- guanosine- 3', 5'- cyclic monophosphate ( BCMCM-caged cGMP )
Caged cyclic GMP, releasing a fluorescent coumarin upon uncaging
Cat. No.: B 017 CAS No.: [339291-52-0]
C24H22N5O15P x 3 H2O; MW 705.5; λmax 347 nm; ε 11200; purity > 98% HPLC. Equatorial isomer, for the corresponding axial isomer or isomeric mixtures please inquire. BCMCM-caged cGMP is an only weakly fluorescent, caged precursor of the second messenger cyclic cGMP, which upon irradiation, releases both cGMP and a fluorescent coumarin analogue. Excellent solubility in water or buffers. Reference: Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).
Protection by patent DE 100 21 256.5 and foreign equivalents
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