Basket (0 Items) - Amount: 0.00$8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-Br-cGMPS )
PDE-resistant analogue of 8-Br-cGMP
Cat. No.: B 006 CAS No.: [153660-03-8]
C10H10BrN5O6PS•Na; MW 462.2; λmax 260 nm; ε 16200; sodium salt, purity > 99% HPLC. For other salt forms please inquire. Unspecific activator of both protein kinase G I α and protein kinase A. Resistant against cyclic nucleotide phosphodiesterases. Much more lipophilic and membrane-permeant compared to cyclic GMP or Sp-cGMPS. Detailed technical information and updated reference list available on request. Reference: Flaadt et al., J. Cell Sci., 105, 255 - 261 (1993).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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