Basket (0 Items) - Amount: 0.00$8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-cGMPS )
PDE-resistant inhibitor of protein kinase G I α and I ß
Cat. No.: B 005 CAS No.: [150418-07-8]
C10H10BrN5O6PS•Na; MW 462.2; λmax 260 nm; ε 16200; sodium salt, purity > 99% HPLC. For other salt forms please inquire. Inhibitor of protein kinase G I α and I ß. Resistant against mammalian cyclic nucleotide- dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane-permeant compared to cyclic GMP or Rp-cGMPS. Detailed technical information and updated reference list available on request. Reference: Zhuo et al., Nature 368, 635 - 639 (1994).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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