Phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins and suitable for modification with fluorophores and other markers. Detailed technical information available. This ligand is also available with a longer spacer (Rp-8-AHA-cAMPS, Cat. No. A 085), and immobilized on agarose gel (Rp-8-AEA-cAMPS, Cat. No. A 007). Reference: Bertinetti et al., BMC Chem. Biol., 9: 3 (2009).
Cat. No. | A 180 |
CAS number | [221904-78-5] |
Purity | > 98% HPLC |
Salt form | Free acid |
Appearance | Solid |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₂H₁₈N₇O₅PS |
Molecular weight [g/mol] | 403.4 |
cAMP modified at the exocyclic oxygen | equatorial (Rp-) |
Modifications | 8-cAMP |
Target | PKA (cAK) Inhibitor |
Lipophilicity | 0.69 |
Absorption max [nm] | 273 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 17000 |
UV pH value | 7 |
Solvent for UV data | Water |