8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 8-AHA-2'-O-Me-cAMP )

C17H28N7O6P; MW 457.4; λmax 273 nm; ε 17000; free acid; purity > 98% HPLC. 8-AHA-2'-O-Me-cAMP has only poor affinity towards protein kinases A and G and is thus suitable as a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Detailed technical information available.
Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
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