8-AHA-2'-O-Me-cAMP has only poor affinity towards protein kinases A and G and is thus suitable as a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Detailed technical information available.
Cat. No. | A 099 |
CAS number | [pending] |
Purity | > 98% HPLC |
Salt form | Free acid |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₇H₂₈N₇O₆P |
Molecular weight [g/mol] | 457.4 |
Modifications | 8-cAMP, 2'-cAMP |
Target | Epac Activator |
Lipophilicity | 1.69 |
Absorption max [nm] | 273 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 17000 |