2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-2'-AHC-cGMPS )
C17H26N7O7PS; MW 503.5; λmax 252 nm; ε 13500; purity > 98% HPLC. PDE-stable cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling structures including fluorophores. Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992). This structure is also offered as a ligand immobilized to agarose (Cat. No. A 052), and without sulfur modification (A 048). Detailed technical information available.
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