Cyclic AMP immobilized on agarose by an aminohexylamino spacer attached to position 2 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a shorter spacer (2-AEA-cAMP-Agarose, Cat. No. A 110) and as PDE-resistant version (Sp-2-AHA-cAMPS-Agarose, Cat. No. A 069). Detailed technical information available. References: Iwitzki, F., PhD Thesis, University of Bremen, Germany, 1993; Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).