2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-AHC-cGMP )
Functionalized cGMP for immobilization or conjugation with markers and dyes
C17H26N7O8P; MW 487.4; λmax 252 nm; ε 13500; purity > 98% HPLC. Cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling structures including fluorophores. Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992). This structure is also offered as a ligand immobilized to agarose (Cat. No. A 059) and with a shorter spacer (2'-AEC-cGMP, Cat. No. A 075). For a corresponding PDE-stable phosphorothioate (Sp-2'-AHC-cGMPS) please refer to Cat. No. A 067. Detailed technical information available.
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