Basket (0 Items) - Amount: 0.00$Adenosine- 3', 5'- monophosphorothioate acetoxymethyl ester, Sp- isomer ( Sp-cAMPS-AM )
Metabolically activatable prodrug of the PDE-resistant PKA agonist Sp-cAMPS
Cat. No.: A 035 CAS No.: [152218-24-1]
C13H16N5O7PS; MW 417.3; λmax 258 nm; ε 15000. Purity > 97% HPLC for mixture of the axial and equatorial isomer. Membrane-permeant precursor of the PDE-resistant protein kinase A activator Sp-cAMPS. Metabolic bioactivation by esterases releases the active analogue, which is trapped inside the cell. Chemical hydrolysis can produce some cyclic AMP as well. Detailed technical information available. Reference: Maronde et al., J. Pineal Res., 31, 183 - 185 (2001).
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
| << Back | Basket (0 Items) >> |