8- (2- Aminophenylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-APT-cGMP )
Isozyme-selective activator of PKG I α
Cat. No.: A 032 CAS No.: [144509-87-5]
C16H16N6O7PS.Na; MW 490.4; λmax 278 nm; ε 18000; sodium salt, purity > 98% HPLC. For other salt forms or metabolites of 8-APT-cGMP please inquire. Isozyme-selective activator of cGMP-dependent protein kinase I a which prefers type I a over I ß by a factor of 200. Detailed technical information with references available. References: Haynes, Br. J. Pharmacol., 130, 685 - 691 (2000); Cook & Haynes, Cell. Signal., 16, 253 - 261 (2004).
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