8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 8-AHA-cAMP Agarose )
Cyclic AMP immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a shorter spacer (8-AEA-cAMP-Agarose, Cat. No. A 020) and as PDE-resistant version (Sp-8-AHA-cAMPS-Agarose, Cat. No. A 013). Detailed technical information available. Reference: Dills et al., Biochemistry, 15, 3724 - 3730 (1976).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
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