Adenosine- 3' ,5'- cyclic monophosphate ( cAMP ), free acid form
C10H12N5O6P; MW 329.2; λmax 258 nm; ε 15000. Free acid form with decreased solubility in aqueous systems, purity > 99% HPLC. Suitable for preparation of lipophilic salt forms. The second messenger cyclic AMP activates protein kinase A, cAMP-gated ion channels, HCN channels, the Epac receptor (cAMP-GEF), the CAP protein and some other target receptors. It is metabolized rapidly by cyclic nucleotide-dependent phosphodiesterases. Detailed technical information available.
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