For other salt forms or higher purity please inquire. Hydrolysis-resistant agonist of the second messenger cyclic ADP ribose (Cat. No. C 005) with increased membrane permeability. Detailed technical information and references available. References: Kirchberger et al., Brit. J. Pharmacol., 149, 337 - 344 (2006); Kirchberger et al., Biochem. J., 422, 139 - 149 (2009).
| Cat. No. | B 071 |
| CAS number | [638195-70-7] |
| Purity | > 97 % HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₅H₁₉BrN₄O₁₄P₂ (free acid) |
| Molecular weight [g/mol] | 621.2 (free acid) |
| Absorption max [nm] | 255 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 11145 |
| UV pH value | 4.9 |
- 1. Kirchberger T., Moreau C., Wagner G. K., Fliegert R., Siebrands C. C., Nebel M., Schmid F., Harneit A., Odoardi F., Flügel A., Potter B. V. L.Guse A. H., Biochem. J., 422, 139 - 149 (2009), "8-Bromo-Cyclic Inosine Diphosphoribose: Towards a Selective Cyclic ADP-Ribose Agonist"
- 2. Kirchberger T., Wagner G., Xu J., Cordiglieri C., Wang P., Gasser A., Fliegert R., Bruhn S., Flügel A., Lund F. E., Zhang L.-H., Potter B. V. L.Guse A. H., Br. J. Pharmacol., 149, 337 - 344 (2006), "Cellular Effects and Metabolic Stability of N1-Cyclic Inosine Diphosphoribose and its Derivatives"
- 3. Guse A. H., FEBS J., 272, 4590 - 4597 (2005), "Second Messenger Function and the Structure-activity Relationship of Cyclic Adenosine Diphosphoribose (cADPR)"
