For other salt forms or higher purity please inquire. ADPR-pNP / ADP-ribose-pNP can be used as a colorimetric substrate to monitor PARP activity. By monitoring the production of p-nitrophenolate, the kinetic parameters of PARP-1, tankyrase, and PARP-4 can be evaluated. Detailed technical information available. Reference: Nottbohm et al., Angew. Chem. Int. Ed., 46, 2066 - 2069 (2007).
| Cat. No. | A 184 |
| CAS number | [939028-75-8] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₂₁H₂₆N₆O₁₆P₂ (free acid) |
| Molecular weight [g/mol] | 680.4 (free acid) |
| Absorption max [nm] | 259 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 15200 |
- 1. Nottbohm A. C., Dothager R. S., Putt K. S., Hoyt M. T.Hergenrother P. J., Angew. Chem. Int. Ed., 46, 2066 - 2069 (2007), "A Colorimetric Substrate for Poly(ADP-Ribose)Polymerase-1, VPARP, and Tankyrase-1"
