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ddT

3'- Deoxythymidine / 2', 3'- Dideoxythymidine ( ddT )
Cat. No.: D 040
    
CAS No.: [3416-05-5]
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Product Name Price (net) Qty
Cat. No.: D 040-100
Unit: 100 µmol / ~23 mg
$100.00
Thymidine analogue of interest in antiviral research. Inhibits DNA polymerase ß and thymidine kinase. Detailed technical information available. References: Yamanaka et al., Biol. Pharmaceut. Bull., 20, 163 - 167 (1997); Seiser et al., J. Mol. Biol., 265, 153 - 160 (1997).
This compound is also part of the Ko-Libri compound library (K 001)
Cat. No. D 040
CAS number [3416-05-5]
Purity > 98% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₄N₂O₄
Molecular weight [g/mol] 226,2
Absorption max [nm] 267
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 9600
  • 1. Sutterluety H.Seiser C., J. Mol. Biol., 265, 153 - 160 (1997), "Thymidine Inhibits the Growth-Arrest-Specific Degradation of Thymidine Kinase Protein in Transfected L Fibroblasts"
  • 2. Yamanaka K., Hayashi H., Kato K., Hasegawa A., Oku N.Okada S., Biol. Pharm. Bull., 20, 163 - 167 (1997), "DNA Single-Strand Breaks in L-132 Cells Resulting from Inhibition of Repair Polymerization Shortly after Exposure to Dimethylarsinic Acid"
  • 3. Buzayan J. M., Feldstein P. A., Segrelles C.Bruening G., Nucleic Acids Res., 16, 4009 - 4023 (1988), "Autolytic Processing of a Phosphorothioate Diester Bond"
  • 4. Suzuki S., Lee B., Luo W., Tovell D., Robins M. J.Tyrrell D. L. J., Biochem. Biophys. Res. Commun., 156, 1144 - 1151 (1988), "Inhibition of Duck Hepatitis B Virus Replication by Purine 2',3'-Dideoxynucleosides"