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ddGTP

2', 3'- Dideoxyguanosine- 5'- O- triphosphate (ddGTP)
Cat. No.: D 019
    
CAS No.: [68726-28-3]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: D 019-05
Unit: 5 µmol / ~2.5 mg
$77.00

For other salt forms or a guaranteed higher purity please inquire. Inhibits DNA polymerase I-dependent chain elongation. Detailed technical information available. Reference: Sanger et al., Proc. Natl. Acad. Sci. USA, 74, 5463 - 5467 (1977).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. D 019
CAS number [68726-28-3]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₀H₁₆N₅O₁₂P₃ (free acid)
Molecular weight [g/mol] 491,2 (free acid)
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13500
  • 1. Sillero M. A., Madrid O., Zaera E.Sillero A., BBA, 1334, 191 - 199 (1997), "2', 3'-Dideoxynucleoside Triphosphates (ddNTP) and di-2',3'-dideoxynucleoside Tetraphosphates (ddNP4ddN) Behave Differently to the Corresponding NTP and Np4N Counterparts as Substrates of Firefly Luciferase, Dinucleoside Tetraphosphatase and Phosphod"
  • 2. Sanger F., Nicklen S.Coulson R., Proc. Natl. Acad. Sci., 74, 5463 - 5467 (1977), "DNA Sequencing with Chain-terminating Inhibitors"
  • 3. Atkinson M. R., Deutscher M. P., Kornberg A., Russell A. F.Moffatt J. G., Biochemistry, 12, 4897 - 4904 (1969), "Enzymatic Synthesis of Deoxribonucleic Acid. XXXIV. Termination of Chain Growth by a 2',3'-Dideoxribonucleotide"