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DB-cAMP

N⁶, 2'- O- Dibutyryladenosine- 3', 5'- cyclic monophosphate ( DB-cAMP ), sodium salt
Metabolically activatable PKA agonist
Cat. No.: D 009
    
CAS No.: [16980-89-5]
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Product Name Price (net) Qty
Cat. No.: D 009-100
Unit: 100 µmol
$50.00
Membrane-permeant activator of protein kinase A (cyclic AMP agonist). Detailed technical information including hints about potential pitfalls and selected references available. Reference: Posternak et al., Methods Enzymol., 38, 399 (1974). Caution: This analogue releases butyrate due to intracellular and extracellular esterase action. Butyrate was shown to have distinct biological effects! We offer numerous more recommendable cAMP agonists.
Cat. No. D 009
CAS number [16980-89-5]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Formula C₁₈H₂₃N₅O₈P · Na
Molecular weight [g/mol] 491,4
Modifications 2'-cAMP
Target PKA (cAK) Activator
Lipophilicity 2.42
Absorption max [nm] 273
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. S. Wolter, S. Dove, M. Golombek, F. Schwede, R. Seifert, Naunyn-Schmiedeberg\'s Arch. Pharmacol., 387, 1163 - 1175 (2014), "N4-monobutyryl-cCMP Activates PKA RIalpha and PKA RIIalpha more Potently and with Higher Efficacy than PKG Ialpha in Vitro but not in Vivo""
  • 2. S. Huseby, H.-G. Genieser, R. Kleppe, S.O. Doeskeland, G. Gausdal, T.J. Keen, E. Kjærland, C. Krakstad, L. Myhren, K. Brønstad, C. Kunick, F. Schwede, Cell Death Dis., e237, 2, 0 - 0 (2011), "Cyclic AMP Induces IPC Leukemia Cell Apoptosis via CRE-and CDK-dependent Bim Transcription""
  • 3. C.S. Spaeth, E.A. Boydston, L.R. Figard, A. Zuzek, G.D. Bittner, J. Neurosci., 30, 15790 - 15800 (2010), "A Model for Sealing Plasmalemmal Damage in Neurons and Other Eukaryotic Cells""
  • 4. M. Desch, E. Schinner, F. Kees, F. Hofmann, R. Seifert, J. Schlossmann, FEBS Lett., 584, 3979 - 3984 (2010), "Cyclic Cytidine 3\',5\'-Monophosphate (cCMP) Signals via cGMP Kinase I""
  • 5. V. Reichel, J. Kläs, G. Fricker, R. Masereeuw, J. Neurochem., 115, 200 - 208 (2010), "Fluo-cAMP is Transported by Multidrug Resistance-associated Protein Isoform 4 in Rat Choroid Plexus""
  • 6. K.A. Scheibner, S. Boodoo, S. Collins, K.E. Black, Y. Chan-Li, P. Zarek, J.D. Powell, M.R. Horton, Am. J. Respir. Cell Mol. Biol., 40, 251 - 259 (2009), "The Adenosine A2a Receptor Inhibits Matrix Induced Inflammation in a Novel Fashion""
  • 7. P. Voisin, M. Bernard, J. Neurochem., 110, 318 - 327 (2009), "Cyclic AMP-dependent Activation of Rhodopsin Gene Transcription in Cultured Retinal Precursor Cells of Chicken Embryo""
  • 8. H.-J. Kwak, K.-M. Park, H.-E. Choi, K.-S. Chung, H.-J. Lim, H.-Y. Park, Cell. Signal., 20, 803 - 814 (2008), "PDE4 Inhibitor Roflumilast Protects Cardiomyocytes against NO-induced Apotosis via Activation of PKA and Epac Dual Pathway""
  • 9. S. Haag, M. Warnken, U.R. Juergens, K. Racke, Naunyn-Schmiedeberg\'s Arch. Pharmacol., 378, 617 - 630 (2008), "Role of Epac1 in Mediating Anti-proliferative Effects of Prostanoid EP2 Receptors and cAMP in Human Lung Fibroblasts""
  • 10. I. Usynin, C. Klotz, U. Frevert, Cell Microbiol., 9, 2610 - 2628 (2007), "Malaria Circumsporozoite Protein Inhibits the Respiratory Burst in Kupffer Cells""
  • 11. M. Brock, F. Fan, F.C. Mei, S. Li, C. Gessner, V.L. Woods, X.D. Cheng, J. Biol. Chem., 282, 32256 - 32263 (2007), "Confirmational Analysis of Epac Activation Using Amide Hydrogen/Deuterium Exchange Mass Spectrometry""
  • 12. J.L. Bos, Trends Biochem. Sci., 31, 680 - 686 (2006), "Epac Proteins: Multi-purpose cAMP Targets""
  • 13. H. Meves, Curr. Neuropharmacol., 4, 41 - 57 (2006), "The Action of Prostaglandins in Ion Channels""
  • 14. S. Fukuhara, A. Sakurai, H. Sano, A. Yamagishi, S. Somekawa, N. Takakura, Y. Saito, K. Kangawa, N. Mochizuki, Mol. Cell. Biol., 25, 136 - 146 (2005), "Cyclic AMP Potentiates Vascular Endothelial Cadherin-mediated Cell-cell Contact to Enhance Endothelial Barrier Function Through an Epac-Rap 1 Signaling Pathway""
  • 15. F. Ohno, J. Watanabe, H. Sekihara, T. Hirabashi, S. Arata, S. Kikuyama, S. Shioda, K. Nakaya, S. Nakajo, Regul. Pept., 126, 115 - 122 (2005), "Pituitary Adenylate Cyclase-activating Polypeptide Promotes Differentiation of Mouse Neural Stem Cells into Astrocytes""
  • 16. F.C. Mei, X.D. Cheng, Molecular Biosystems, 1, 325 - 331 (2005), "Interplay between Exchange Protein Directly Activated by cAMP (Epac) and Microtubule Cytoskeleton""
  • 17. S.P. Sakhalkar, E.B. Patterson, M.M. Khan, Int. J. Immunopharmacol., 5, 1299 - 1309 (2005), "Involvement of Histamine H1 and H2 Receptors in the Regulation of STAT-1 Phosphorylation: Inverse Agonism Exhibited by the Receptor Antagonists""
  • 18. F.C. Britz, J.C. Hirth, J.W. Deitmer, Eur. J. Neuroscience, 19, 983 - 992 (2004), "Second messenger cascade of glial responses evoked by interneuron activity and by a myomodulin peptide in the leech central nervous system.\r\n""
  • 19. A.V. Makarevich, A.V. Sirotkin, H.-G. Genieser, Anim. Reprod. Sci., 81, 125 - 136 (2004), "Action of Protein Kinase A Regulators on Secretory Activity of Porcine Granulosa Cells in Vitro""
  • 20. M.G. Rondaij, E. Sellink, K.A. Gijzen, J.P. Ten Klooster, P.L. Hordijk, J.A. Van Mourik, J. Voorberg, Arterioscler. Thromb. Vasc. Biol., 24, 1315 - 1320 (2004), "Small GTP-Binding Protein Ral is Involved in cAMP-mediated Release of von Willebrand Factor From Endothelial Cells""
  • 21. F. Lemtiri-Chlieh, G.A. Berkowitz, J. Biol. Chem., 279, 35306 - 35312 (2004), "Cyclic Adenosine Monophosphate Regulates Calcium Channels in the Plasma Membrane of Arabidopsis Leaf Guard and Mesophyll Cells""
  • 22. D.H. Bhatt, S.J. Otto, B. Depoister, J.R. Fetcho, Science, 305, 254 - 258 (2004), "Cyclic AMP-Induced Repair of Zebrafish Spinal Circuits""
  • 23. S. Sanada, M. Fujita, A. Hirata, H. Okuda, H. Shimokawa, H. Tomoike, M. Hori, M. Kitakaze, H. Asanuma, O. Tsukamoto, T. Minamino, K. Node, S. Takashima, T. Fukushima, A. Ogai, Y. Shinozaki, Circulation, 110, 51 - 57 (2004), "Protein Kinase A as Another Mediator of Ischemic Preconditioning Independent of Protein Kinase C""
  • 24. F. Okamoto, H. Kajiya, H. Fukushima, E. Jimi, K. Okabe, Am. J. Physiol.-Cell Physiol., 287, 114 - 124 (2004), "Prostaglandin E-2 Activates Outwardly Rectifying Cl-channels via a cAMP-dependent Pathway and reduces Cell motility in Rat Osteoclasts""
  • 25. C. O\'Flaherty, E. de Lamirande, C. Gagnon, Mol. Hum. Reprod., 10, 355 - 363 (2004), "Phosphorylation of the Arginine-X-X-(serine/threonine) Motif in Human Sperm Proteins During Capacitation: Modulation and Protein Kinase A Dependency""
  • 26. B. Marquez, S.S. Suarez, Biol. Reprod., 70, 1626 - 1633 (2004), "Different Signaling Pathways in Bovine Sperm Regulate Capacitation and Hyperactivation""
  • 27. H. Jing, J.H. Yen, D. Ganea, J. Biol. Chem., 279, 55176 - 55186 (2004), "A Novel Signaling Pathway Mediates the Inhibition of CCL3/4 Expression by PGE2""
  • 28. F.S. Chen, T. Nakamura, H. Wada, Yonsei Med. J., 45, 1107 - 1114 (2004), "Development of New Organ Preservation Solutions in Kyoto University""
  • 29. M. Bartsch, M. Zorn-Kruppa, N. Kühl, H.-G. Genieser, F. Schwede, B. Jastorff, Biol. Chem., 384, 1321 - 1326 (2003), "Bioactivatable, Membrane-permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells""
  • 30. J. Lara, K. Kusano, S. House, H. Gainer, Exp. Neurol., 180, 32 - 5 (2003), "Interactions of Cyclic Adenosine Monophosphate, Brain-Derived Neutrotrophic Factor, and Glial Cell Line-Derived Neurotrophic Factor Treatment on the Survival and Growth of Postnatal Mesencephalic Dopamine Neurons in Vitro""
  • 31. K. Kageyama, K.I. Furukawa, I. Miki, K. Terui, S. Motomura, T. Suda, J. Cardiovasc. Pharmacol., 42, 561 - 565 (2003), "Vasodilative Effects of Urocortin II via Protein Kinase A and a Mitogen-activated Protein Kinase in Rat Thoracic Aorta""
  • 32. A.A. Steiner, J. Antunes-Rodrigues, L.G.S. Branco, Brain Res., 944, 135 - 145 (2002), "Role of Preoptic Second Messenger Systems (cAMP and cGMP) in the Febrile Response""
  • 33. C.A. Johnston, M.A. Beazely, A.F. Vancura, J.K.T. Wang, V.J. Watts, J. Neurochem., 82, 1087 - 1096 (2002), "Heterologous Sensitization of Adenylate Cyclase is Protein Kinase A-dependent in Cath.a Differentiated (CAD)-D-2L Cells""
  • 34. F.C. Mei, J. Qiao, O.M. Tsygankova, J.L. Meinkoth, L.A. Quilliam, X. Cheng, J. Biol. Chem., 277, 11497 - 11504 (2002), "Differential Signaling of cyclic AMP: Opposing Effects of Exchange Protein Directly Activated by cyclic AMP and cAMP-dependent Protein Kinase on Protein Kinase B Activation""
  • 35. J. Gomez-Ramirez, J. Ortiz, I. Blanco, Mol. Pharmacol., 61, 239 - 245 (2002), "Presynaptic H-3 Autoreceptors Modulate Histamine Synthesis through cAMP Pathway""
  • 36. K. Nasu, K. Arima, K. Fujisawa, M. Nishida, K. Kai, I. Miyakawa, Fert. Steril., 77, 392 - 395 (2002), "Secretion of Keratinocyte Growth Factor by Cultured Human Endometrial Stromal Cells is Induced through a Cyclic Adenosine Monophosphate-dependent Pathway""
  • 37. M. Amemiya, E. Kusano, S. Muto, K. Tabei, Y. Ando, R.J. Alpern, Y. Asano, Exp. Nephrol., 10, 26 - 33 (2002), "Glucagon Acutely Inhibits but Chronically Activates Na+/H+ Antiporter 3 Activity in OKP Cells""
  • 38. D. Levy, A.M. Strassman, J. Physiol.-London, 538, 483 - 493 (2002), "Distinct Sensitizing Effects of the cAMP-PKA Second Messenger Cascade on Rat Dural Mechanonociceptors""
  • 39. E.A. Bukharaeva, D. Samigullin, E. Nikolsky, F. Vyskocil, J. Physiol.-London, 538, 837 - 848 (2002), "Protein Kinase A Cascade Regulates Quantal Release Dispersion at Frog Muscle Endplate""
  • 40. K.C. Bagley, S.F. Abdelwahab, R.G. Tuskan, T.R. Fouts, G.K. Lewis, Infect. Immun., 70, 5533 - 5539 (2002), "Cholera Toxin and Heat-Labile Enterotoxin Activate Human Monocyte-derived Dendritic Cells and Dominantly Inhibit Cytokine Production through a Cyclic AMP-dependent Pathway""
  • 41. S. Yamada, M. Komatsu, Y. Sato, K. Yamauchi, I. Kojima, T. Aizawa, K. Hashizume, Endocrinology, 143, 4203 - 4209 (2002), "Time-dependent Stimulation of Insulin Exocytosis by 3\', 5\'-cyclic Adenosine Monophosphate in the Rat Islet Beta-Cell""
  • 42. K. Abe, R. Hosoi, S. Momosaki, K. Kobayashi, N. Ibii, O. Inoue, Brain Res., 952, 211 - 217 (2002), "Increment of in Vivo Binding of [H-3]SCH 23390, a Dopamine D-1 Receptor Ligand, Induced by Cyclic AMP-dependent Protein Kinase in Rat Brain""
  • 43. J. Matuszyk, M. Cebrat, W. Kalas, L. Strzadala, Int. Immunopharmacol., 2, 435 - 442 (2002), "HA1004, an Inhibitor of Serine/Threonine Protein Kinases, Restores the Sensitivity of Thymic Lymphomas to Ca2+-mediated Apoptosis through a Protein Kinase A-independent Mechanism""
  • 44. Q. Leng, R.W. Mercier, B.-G. Hua, H. Fromm, G.A. Berkowitz, Plant Physiol., 128, 400 - 410 (2002), "Electrophysical Analysis of Cloned Cyclic Nucleotide-Gated Ion Channels""
  • 45. C. Martinez, M. Sanchez, A. Hidalgo, M.J.G. de Boto, Eur. J. Pharmacol., 413, 109 - 116 (2001), "Involvement of K-ATP Channels in Diethylstilbestrol-induced Relaxation in Rat Aorta""
  • 46. H. Onuma, C. Mastui, M. Morohashi, Arch. Dermatol. Res., 293, 133 - 138 (2001), "Quantitative Analysis of the Proliferation of Epidermal Cells Using a Human Skin Organ Culture System and the Effect of DbcAMP Using Markers of Proliferation (BrdU, Ki-67, PCNA)""
  • 47. L.A. de la Rosa, N. Vilarino, M.R. Vieytes, L.M. Botana, Cell. Signal., 13, 441 - 449 (2001), "Modulation of Thapsigargin-induced Calcium Mobilisation by Cyclic AMP-elevating Agents in Human Lymphocytes is Insensitive to the Action of the Protein Kinase A Inhibitor H-89""
  • 48. U.T. Shankavaram, W.C. Lai, S. Netzel-Arnett, P.R. Mangan, J.A. Ardans, N. Caterina, W.G. Stetler-Stevenson, H. Birkedal-Hansen, L.M. Wahl, J. Biol. Chem., 276, 19027 - 19032 (2001), "Monocyte Membrane Type 1-Matrix Metalloproteinase - Prostaglandin-dependent Regulation and Role in Metalloproteinase-2 Activation""
  • 49. Y. Koyano, Y. Kato, T. Kawamoto, A. Kikuchi, M. Shen, Y. Kuruta, S. Tsutsumi, K. Fujimoto, M. Noshiro, K. Fujii, Osteoarthritis Cartilage, 9, 64 - 68 (2001), "Chondrocyte-derived Ezrin-like Domain Containing Protein (CDEP), a Rho Guanine Nucleotide Exchange Factor, Is Inducible in Chondrocytes by Parathyroid Hormone and Cyclic AMP and Has Transforming Activity in NIH3T3 Cells""
  • 50. S. Bordin, X. Tan, Cell. Signal., 13, 119 - 123 (2001), "C1q Arrests the Cell Cycle Progression of Fibroblasts in G(1) Phase: Role of the cAMP/PKA-I Pathway""
  • 51. M. Yanagisawa, K. Suzuki, Jpn. J. Physiol., 51, 355 - 363 (2001), "A Reciprocal Regulation of Ca2+-activated K+ Channel by Insulin and Somatostatin in Guinea-Pig Pancreatic Acinar Cells""
  • 52. H. Iber, L.M. Tong, C.H. Qi, Y. Sheng, E.T. Morgan, J. Pharmacol. Exp. Ther., 297, 174 - 180 (2001), "Regulation of Hepatic Cytochrome P450 2C11 via cAMP: Implications for Down-Regulation in Diabetes, Fasting, and Inflammation""
  • 53. J.C. Fleischhauer, C.H. Mitchell, K. Peterson-Yantorno, M. Coca-Prados, M.M. Civan, Am. J. Physiol.-Cell Physiol., 281, 1614 - 1623 (2001), "PGE2, Ca2+, and cAMP Mediate ATP Activation of Cl- Channels in Pigmented Ciliary Epithelial Cells""
  • 54. Y. Hayabuchi, C. Dart, N.B. Standen, J. Physiol.-London, 536, 421 - 427 (2001), "Evidence for Involvement of A-Kinase Anchoring Protein in Activation of Rat Arterial K-ATP Channels by Protein Kinase A""
  • 55. S. Akbar, T. Minor, Cell. Mol. Life Sci., 58, 1708 - 1714 (2001), "Significance and Molecular Targets of Protein Kinase A During cAMP-mediated Protection of Cold Stored Liver Grafts""
  • 56. R. Hosoi, S. Momosaki, N. Ibii, K. Abe, T. Itoh, O. Inoue, Brain Res., 921, 260 - 263 (2001), "The Role of the cAMP-PKA System in the Short-Term Regulation of Striatal [C-14]-2-Deoxyglucose Uptake in Freely Moving Rats""
  • 57. A.T. Grazul-Bilska, L.P. Reynolds, J.J. Bilski, D.A. Redmer, Biol. Reprod., 65, 777 - 783 (2001), "Effects of Second Messengers on Gap Junctional Intercellular Communication of Ovine Luteal Cells throughout the Estrous Cycle""
  • 58. M.C. Martin, I. Dransfield, C. Haslett, A.G. Rossi, J. Biol. Chem., 276, 45041 - 45050 (2001), "Cyclic AMP Regulation of Neutrophil Apoptosis Occurs via a Novel Protein Kinase A-independent Signaling Pathway""
  • 59. C.M. Brophy, D.A. Woodrum, J. Pollock, M. Dickinson, P. Komalavilas, T.L. Cornwell, T.M. Lincoln, J. Vasc. Res., 39, 95 - 103 (2001), "cGMP-dependent Protein Kinase Expression Restores Contractile Function in Cultured Vascular Smooth Muscle Cells""
  • 60. D. Communi, R. Janssens, B. Robaye, N. Zeelis, J.M. Boeynaems, Drug Develop. Res., 52, 156 - 163 (2001), "Role of P2Y 11 Receptors in Heamatopoisis""
  • 61. W. Xu, A.T. Marshall, J. Insect Physiol., 46, 21 - 31 (2000), "Control of Ion and Fluid Transport by Putative Second Messengers in Different Segments of the Malpighian Tubules of the Black Field Cricket Teleogryllus oceanicus""
  • 62. M. Kimura, T. Osanai, K. Okumura, S. Suga, T. Kanno, N. Kamimura, N. Horiba, M. Wakui, Cell. Signal., 12, 63 - 70 (2000), "Involvement of Phosphorylation of Beta-Subunit in cAMP-Dependent Activation of L-Type Ca2+ Channel in Aortic Smooth Muscle-Derived A7r5 Cells""
  • 63. A.V. Sirotkin, D. Mertin, K. Süvegova, A.V. Makarevich, H.-G. Genieser, M.R. Luck, L.V. Osadchuk, Gen. Comp. Endocrinol., 117, 207 - 217 (2000), "Effect of Restricted Food Intake on Production, Catabolism, and Effects of IGF-I and Cyclic Nucleotides in Cultured Ovarian Tissue of Domestic Nutria (Myocastor coypus)""
  • 64. C.L. Thompson, G. Razzini, S. Pollard, F.A. Stephenson, J. Neurochem., 74, 920 - 931 (2000), "Cyclic AMP-Mediated Regulation of GABA(A) Receptor Subunit Expression in Mature Rat Cerebellar Granule Cells: Evidence for Transcriptional and Translational Control""
  • 65. T. Bando, J.M. Albes, J. Schöne, H. Wada, S. Hitomi, T. Wahlers, H.J. Schefers, Ann. Thorac. Surg., 69, 887 - 891 (2000), "Significance of Cyclic Adenosine Monophosphate and Nitroglycerin in ET-Kyoto Solution for Lung Preservation""
  • 66. G. Dawson, Int. J. Dev. Neurosci., 18, 247 - 257 (2000), "Mechanisms of Apoptosis in Embryonic Cortical Neurons (E6 and E7) in Culture Involve Lipid Signalling, Protein Phosphorylation and Caspase Activation""
  • 67. G.E. Vicentini, J. Constantin, C.H. Lopez, A. Bracht, Biochem. Pharmacol., 59, 1187 - 1201 (2000), "Transport of Cyclic AMP and Synthetic Analogs in the Perfused Rat Liver""
  • 68. N. Oki, S.-I. Takahashi, H. Hidaka, M. Conti, J. Biol. Chem., 275, 10831 - 10837 (2000), "Short Term Feedback Regulation of cAMP in FRTL-5 Thyroid Cells - Role of PDE4D3 Phosphodiesterase Activation""
  • 69. K. Wirkner, H. Assmann, L. Koles, Z. Gerevich, H. Franke, W. Norenberg, R. Boehm, P. Illes, Br. J. Pharmacol., 130, 259 - 269 (2000), "Inhibition of Adenosine A(2A) receptors of NMDA but not AMPA Currents in Rat Neostriatal Neurons""
  • 70. K.W. Braun, W.A. Tribley, M.D. Griswold, K.H. Kim, J. Biol. Chem., 275, 4145 - 4151 (2000), "Follicle-stimulating Hormone Inhibits All-trans-retinoic Acid-induced Retinoic Acid Receptor alpha Nuclear Localization and Transcriptional Activation in Mouse Sertoli Cell Lines""
  • 71. M. Zaccolo, F. De Giorgi, C.Y. Cho, L. Feng, T. Knapp, P.A. Negulescu, S.S. Taylor, R.Y. Tsien, T. Pozzan, Nature Cell Biol., 2, 25 - 29 (2000), "A Genetically Encoded, Fluorescent Indicator for Cyclic AMP in Living Cells""
  • 72. A. Wang, J.A. Martin, L.A. Lembke, R.J. Midura, J. Biol. Chem., 275, 11082 - 11091 (2000), "Reversible Suppression of In Vitro Biomineralization by Activation of Protein Kinase A""
  • 73. L. Uphouse, S. Maswood, A. Jackson, Pharmacol. Biochem. Behav., 66, 383 - 388 (2000), "Factors Elevating cAMP Attenuate the Effects of 8-OH-DPAT on Lordosis Behavior""
  • 74. R. Omar, F.E. Bottrill, C.R. Hiley, R. White, Eur. J. Pharmacol., 401, 85 - 96 (2000), "Interaction of Cyclic AMP Modulating Agents with Levcromakalim in the Relaxation of Rat Isolated Mesenteric Artery""
  • 75. M. Suzuki, K. Ishibashi, G. Ooki, S. Tsuruoka, M. Imai, Biochem. Biophys. Res. Commun., 274, 344 - 349 (2000), "Electrophysiologic Characteristics of the Ca-Permeable Channels, ECaC and CaT, in the Kidney""
  • 76. T.A. Churchill, B.M. Wu, D.F. Mercer, N.M. Kneteman, J. Hepatol., 32, 473 - 480 (2000), "The Role of Protein Kinase A in Anaerobic Energy Production During Liver Storage""
  • 77. F. Schwede, E. Maronde, H.-G. Genieser, B. Jastorff, Pharmacol. Ther., 87, 199 - 226 (2000), "Cyclic Nucleotide Analogs as Biochemical Tools and Prospective Drugs""
  • 78. L-.J. Zhou, I. Ono, Br. J. Dermatol., 143, 506 - 512 (2000), "Stimulatory Effects of Dibutyryl Cyclic Adenosine Monophosphate on Cytokine Production by Keratinocytes and Fibroblasts""
  • 79. D.R. Giovannucci, G.E. Groblewski, J. Sneyd, D.I. Yule, J. Biol. Chem., 275, 33704 - 33711 (2000), "Targeted Phosphorylation of Inositol 1,4,5-Triphosphate Receptors Selectively Inhibits Localized Ca2+ Release and Shapes Oscillatory Ca2+ Signals""
  • 80. E. Pereyra, C. Mizyrycki, S. Moreno, Microbiology-(UK), 146, 1949 - 1958 (2000), "Threshold Level of Protein Kinase A Activity and Polarized Growth in Mucor rouxii""
  • 81. J. Li, S. Yang, T.R. Billiar, J. Biol. Chem., 275, 13026 - 13034 (2000), "Cyclic Nucleotides Suppress Tumor Necrosis Factor Alpha-Mediated Apoptosis by Inhibiting Caspase Activation and Cytochrome c Release in Primary Hepatocytes via a Mechanism Independent of Akt Activation""
  • 82. H. Harayama, M. Miyake, S. Kato, Reprod. Fertil. Dev., 12, 307 - 318 (2000), "Role of Cyclic Adenosine 3\',5\'-Monophosphate and Serum Albumin in Head-to-head Agglutination of Boar Spermatozoa""
  • 83. N. Samih, S. Hovsepian, A. Aouani, D. Lombardo, G. Fayet, Endocrinology, 141, 4146 - 4155 (2000), "Glut-1 Translocation in FRTL-5 Thyroid Cells: Role of Phosphatidylinositol 3-Kinase and N-Glycosylation""
  • 84. M. Arai, R.G. Thurman, J.J. Lemasters, Hepatology, 32, 297 - 302 (2000), "Contribution of Adenosine A2 Receptors and Cyclic Adenosine Monophosphate to Protective Ischemic Preconditioning of Sinusoidal Endothelial Cells Against Storage/Reperfusion Injury in Rat Livers""
  • 85. A.V. Sirotkin, D. Mertin, K. Süvegova, A.V. Makarevich, H.-G. Genieser, L.V. Osadchuk, Animal Production Review, 0, 0 - 0 (2000), "The Cyclic Nucleotide-IGF-I System as Possible Mediator of Effect of Nutrition on Ovarian Activity in Domestic Nutria (Myocastor coypus)""
  • 86. C.Y. Wang, D.J. Pinsky, I. Aronson, S. Takuma, S. Homma, Y. Naka, T. Alshafie, V. Brovkovych, T. Malinski, M.C. Oz, Circ. Res., 86, 982 - 988 (2000), "cAMP Pulse During Preservation Inhibits the Late Development of Cardiac Isograft and Allograft Vasculopathy""
  • 87. W.M. MacKenzie, D.W. Hoskin, J. Blay, Biochem. Biophys. Res. Commun., 255, 460 - 465 (1999), "The Adhesion of Anti-CD3-Activated Mouse T Cells to Syngeneic Colon Adenocarcinoma Cells is Differentially Regulated by Protein Tyrosine Kinase-, Protein Kinase C-, and cAMP-Dependent Pathways in the Effector Cell""
  • 88. P.J. Bryce, M.J. Dascombe, I.V. Hutchinson, Immunopharmacology, 41, 139 - 146 (1999), "Immunomodulatory Effects of Pharmacological Elevation of Cyclic AMP in T Lymphocytes Proceed Via a Protein Kinase A Independent Mechanism""
  • 89. M. Cytrynska, I. Wojda, M. Frajnt, T. Jakubowicz, Can. J. Microbiol., 45, 31 - 37 (1999), "PKA from Saccharomyces Cerevisiae can be Activated by Cyclic AMP and Cyclic GMP""
  • 90. B.D. Murphy, M. Dobias, Mol. Reprod. Dev., 53, 198 - 207 (1999), "Homologous and Heterologous Ligands Downregulate Follicle-Stimulating Hormone Receptor mRNA in Porcine Granulosa Cells""
  • 91. L. McMartin, R.J. Summers, Br. J. Pharmacol., 127, 1012 - 1020 (1999), "Functional Analysis of Desensitization of the Beta-Adrenoceptor Signalling Pathway in Rat Cardiac Tissues Following Chronic Isoprenaline Infusion""
  • 92. M. Galisteo, N. Marc, A. Fautrel, A. Guillouzo, L. Corcos, D. Lagadic-Gossmann, J. Pharmacol. Exp. Ther., 290, 1270 - 1277 (1999), "Involvement of Cyclic Nucleotide- and Calcium-Regulated Pathways in Phenobarbital-Induced Cytochrome P-450 3A Expression in Mouse Primary Hepatocytes""
  • 93. S.G. Dedos, H. Fugo, Mol. Cell. Endocrinol., 154, 63 - 70 (1999), "Interactions between Ca2+ and cAMP in Ecdysteroid Secretion from the Prothoracic Glands of Bombyx mori""
  • 94. A. Samokovlisky, G. Rimon, A. Danon, Eur. J. Pharmacol., 378, 203 - 211 (1999), "Differential Regulation of Cyclooxygenase Isozymes by cAMP-Elevating Agents""
  • 95. T.A. Shahan, N. Ohno, S. Pasco, J.P. Borel, J.-C. Monboisse, N.A. Kefalides, Connect. Tissue Res., 40, 221 - 232 (1999), "Inhibition of Tumor Cell Proliferation by Type IV Collagen Requires Increased Levels of cAMP""
  • 96. N. Niisato, Y. Ito, Y. Marunaka, Life Sci., 65, 109 - 114 (1999), "Effect of PKA Inhibitors, H-compounds, on Epithelial Na+ Channels Via PKA-independent Mechanisms""
  • 97. L. Zhang, E. Karpinski, C.G. Benishin, Neurochem. Int., 35, 345 - 355 (1999), "Prostaglandin E-2 Modulates a Non-Inactivating Potassium Current in Rat Neurohypophyseal Nerve Terminals""
  • 98. H. Shimura, T. Midorikawa, Y. Yoshizawa, Y. Sanada, H. Ohata, H. Sakagami, M. Takeda, M. Yamaguchi, M. Kuzume, A. Matsumiya, T. Matsumoto, H. Sakai, T. Hatakeyama, H. Nakano, K. Kumada, Eur. Surg. Res., 31, 390 - 398 (1999), "Prevention of Reactive Oxygen-Induced Endothelial Cell Injury by Blocking its Process""
  • 99. M. Grimaldi, A. Favit, D. L. Alkon, J. Biol. Chem., 274, 33557 - 33564 (1999), "cAMP-Induced Cytoskeleton Rearrangement Increases Calcium Transients through the Enhancement of Capacitative Calcium Entry""
  • 100. T. Mano, M. Wada, A. Nagasaka, M. Itoh, K. Uchimura, R. Hayashi, T. Kobahashi, K. Fujiwara, M. Makino, H. Kakizawa, M. Nagata, A. Nakai, Horm. Metab. Res., 31, 602 - 605 (1999), "Increased Urinary Phosphate Excretion in Pseudohypoparathyroidism Type II with Long-Term Treatment with Phosphodiesterase Inhibitor""
  • 101. O.M. Seternes, R. Sorensen, B. Johansen, U. Moens, Cell. Signal., 11, 211 - 219 (1999), "Activation of Protein Kinase A by Dibutyryl cAMP Treatment of NIH 3T3 Cells Inhibits Proliferation but Fails to Induce Ser-133 Phosphorylation and Transcriptional Activation of CREB""
  • 102. Q. Leng, R.W. Mercier, W.Z. Yao, G.A. Berkowitz, Plant Physiol., 121, 753 - 761 (1999), "Cloning and First Functional Characterization of a Plant Cyclic Nucleotide-gated Cation Channel""
  • 103. D. Mertin, A.V. Sirotkin, K. Süvegova, A.V. Makarevich, H.-G. Genieser, M.R. Luck, L.V. Osadchuk, Society for the Study of Fertility Aberystwyth, 32, 0 - 0 (1999), "The Cyclic Nucleotide - IGF-I System as a Possible Link Between Nutrion and Reproduction in Domestic Nutria""
  • 104. M.S. Taylor, A.M. McMahon, J.D. Gardner, J.N. Benoit, Pathophysiology, 5, 233 - 245 (1999), "Cyclic nucleotides and vasoconstrictor function: physiological and pathophysiological considerations""
  • 105. Y.S. Cho-Chung, B. Jastorff, H.-G. Genieser, USA patent 5916, 843, 0 - 0 (1998), "Cyclic AMP Analogues, Individually and in Pairs, to Inhibit Neoplastic Cell Growth""
  • 106. F. Gantner, C. Gotz, V. Gekeler, C. Schudt, A. Wendel, A. Hatzelmann, Br. J. Pharmacol., 123, 1031 - 1038 (1998), "Phosphodiesterase Profile of Human B Lymphocytes from Normal and Atopic Donors and the Effects of PDE Inhibition on B Cell Proliferation""
  • 107. K. Kurosaki, U. Ikeda, Y. Maeda, M. Shimpo, S. Ueno, K. Shimada, Cardiovasc. Res., 38, 192 - 197 (1998), "Effects of Vesnarinone on Nitric Oxide Synthesis in Rat Cardiac Myocytes""
  • 108. T.A. Wyatt, J.R. Spurzem, K. May, J.H. Sisson, Amer. J. Physiol.- Lung Cell Mol. Physiol., 19, 827 - 835 (1998), "Regulation of Ciliary Beat Frequency by both PKA and PKG in Bovine Airway Epithelial Cells""
  • 109. J.D. Militante, J.B. Lombardini, Amino Acids, 15, 99 - 108 (1998), "Pharmacological Characterization of the Effects of Taurine on Calcium Uptake in the Rat Retina""
  • 110. L.Y. Poluektova, M.M. Khan, Immunopharmacology, 39, 9 - 19 (1998), "Protein Kinase A Inhibitors Reverse Histamine-Mediated Regulation of IL-5 Secretion""
  • 111. C.P. Tran, M. Familari, L.M. Parker, R.H. Whitehead, A.S. Giraud, Amer. J. Physiol., 38, 85 - 94 (1998), "Short-chain Fatty Acids Inhibit Intestinal Trefoil Factor Gene Expression in Colon Cancer Cells""
  • 112. T. Ono, I. Matsuoka, S. Ohkubo, J. Kimura, H. Nakanishi, Jpn. J. Pharmacol., 78, 269 - 277 (1998), "Effects of YT-146[2-(-octynyl)adenosine], an Adenosine A(2A) Receptor Agonist, on cAMP Production and Noradrenaline Release in PC12 Cells""
  • 113. Y.S. Cho-Chung, R.K. Robins, United States Patent 5752 of August 11, 792, 0 - 0 (1998), "8-Chloro cAMP and Related cAMP Compounds as Antineoplastic Agents""
  • 114. D.W. Self, L.M. Genova, B.T. Hope, W.J. Barnhart, J.J. Spencer, E.J. Nestler, J. Neurosci., 18, 1848 - 1859 (1998), "Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behaviour""
  • 115. R. Goswami, S.A. Dawson, G. Dawson, J. Neurochem., 70, 1376 - 1382 (1998), "Cyclic AMP Protects Against Staurosporine and Wortmannin-Induced Apoptosis and Opioid-Enhanced Apoptosis in Both Embryonic and Immortalized (F-11-Kappa-7) Neurons""
  • 116. T. Kanno, S. Suga, J. Wu, M. Kimura, M. Wakui, Pflugers Arch.- Eur. J. Physiol, 435, 578 - 580 (1998), "Intracellular cAMP Potentiates Voltage-Dependent Activation of L-Type CA2+ Channels in Rat Islet Beta-Cells""
  • 117. D.W. Ali, S. Catarsi, P. Drapeau, J. Physiol.-London, 509, 211 - 219 (1998), "Ionotropic and Metabotropic Activation of a Neuronal Chloride Channel by Serotonin and Dopamine in the Leech Hirudo Medicinalis""
  • 118. K.C. Fernando, R.B. Gregory, G.J. Barritt, Biochem. J., 330, 1179 - 1187 (1998), "Protein Kinase A Regulates the Disposition of CA2+ which Enters the Cytoplasmic Space through Store-Activated CA2+ Channels in Rat Hepatocytes by Deverting
  • 119. J. Myslivecek, V. Lisa, S. Trojan, S. Tucek, Life Sci., 63, 1169 - 1182 (1998), "Heterologous Regulation of Muscarinic and Beta-Adrenergic Receptors in Rat Cardiomyocytes in Culture""
  • 120. M.L. Carranza, M. Rousselot, A.V. Chibalin, A.M. Bertorello, H. Favre, E. Feraille, J. Physiol.- London, 511, 235 - 243 (1998), "Protein Kinase A Induces Recruitment of Active NA+, K+ATPase Units to the Plasma Membrane of Rat Proximal Convoluted Tubule Cells""
  • 121. M. Kanatani, T. Sugimoto, Y. Takahashi, H. Kaji, R. Kitazawa, K. Chihara, J. Bone Miner. Res., 13, 854 - 862 (1998), "Estrogen via the Estrogen Receptor Blocks cAMP-Mediated Parathyroid Hormone (PTH)-Stimulated Osteoclast Formation""
  • 122. C.D. Jun, H.O. Pae, J.C. Yoo, H.J. Kwak, R.K. Park, H.T. Chung, Cell. Immunol., 183, 13 - 21 (1998), "Cyclic Adenosine Monophosphate Inhibits Nitric Oxide-Induced Apoptosis in Human Leukemic HL-60 Cells""
  • 123. L. Jiang, F.M. Foster, P. Ward, V. Tasevski, B.M. Luttrell, A.D. Conigrave, Biochem. Biophys. Res. Commun., 236, 626 - 630 (1997), "Extracellular ATP Triggers Cyclic AMP-Dependent Differentiation of HL-60 Cells""
  • 124. K. Anciaux, K. Van Dommelen, S. Nicolai, E. Van Mechelen, H. Slegers, J. Neurosci. Res., 48, 324 - 333 (1997), "Cyclic AMP-Mediated Induction of the Glial Fibrillary Acidic Protein is Independent of Protein Kinase A Activation in Rat C6 Glioma""
  • 125. A. Sjöholm, Diabetes, 46, 1141 - 1147 (1997), "Glucose Stimulates Islet ß-Cell Mitogenesis Through GTP Binding Proteins and by Protein Kinase C-Dependent Mechanisms""
  • 126. E.M. Weissinger, H. Mischak, W. Kolch, G. Eissner, C. Grammer, S. Fackler, B. Haefner, L.S. Yoon, K.S. Lu, A. Bazarow, J.M. Sedivy, Mol. Cell. Biol., 17, 3229 - 3241 (1997), "Inhibition of the Raf-1 Kinase by Cyclic AMP Agonists Causes Apoptosis of v-abl-Transformed Cells""
  • 127. H. Müller, R. Liu, F. David, U. Eppenberger, Biol. Chem., 378, 1023 - 1029 (1997), "Selective Modulation of Protein Kinase A and Protein Kinase C Activities in Epidermal Growth Factor (EGF)-Stimulated MCF-7 Breast Cancer Cells""
  • 128. G. Fassina, M.G. Aluigi, S. Gentleman, P. Wong, T.N. Cai, A. Albini, D.M. Noonan, Int. J. Cancer, 72, 1088 - 1094 (1997), "The cAMP Analog 8-Cl-cAMP Inhibits Growth And Induces Differentiation And Apoptosis In Retinoblastoma Cells.""
  • 129. G. Picotto, V. Massheimer, R. Boland, Amer. J. Physiol.-Cell Physiol., 42, 1349 - 1353 (1997), "Parathyroid Hormone Stimulates Calcium Influx And The cAMP Messenger System In Rat Enterocytes""
  • 130. T. Kline, P.F. Pollice, R.N. Rosier, P.R. Reynolds, J.E. Puzas, R.J. Okeefe, J. Bone Joint Surg.- Amer. Vol., 79, 1519 - 1528 (1997), "Modulation of the Production of Cytokines in Titanium-Stimulated Human Peripheral Blood Monocytes by Pharmacological Agents - The Role of cAMP-Mediated Signaling Mechanisms""
  • 131. Y. Mio, S. Suga, T. Osanai, T. Kanazawa, K. Onodera, J. Wada, N. Kamimura, M. Wakui, Cell. Signal., 9, 367 - 372 (1997), "Oxidized LDLS But Not Native LDL Augment BA2+ Currents Through L-Type CA2+ Channels Of The A7R5 Smooth Muscle-Derived Cell Line""
  • 132. S. Jenab, C.E. Inturrisi, Mol. Brain Res., 47, 44 - 48 (1997), "Activation of Protein Kinase A Prevents the Ethanol-Induced Up-Regulation of Delta Opioid Receptor MRNA In NG108-15 Cells""
  • 133. S. Suga, T. Kanno, K. Nakano, T. Takeo, Y. Dobashi, M. Wakui, Diabetes, 46, 1755 - 1760 (1997), "GLP-I(7-36) Amide Augments Ba2+ Current Through L-Type Ca2+ Channel of Rat Pancreatic Beta-Cell in a cAMP-Dependent Manner.""
  • 134. H. Kaji, T. Sugimoto, M. Kanatani, K. Nishiyama, M. Nasu, K. Chihara, J. Cell. Physiol., 172, 55 - 62 (1997), "Insulin-Like Growth Factor-1 Mediates Osteoclast-Like Cell Formation Stimulated By Parathyroid Hormone.""
  • 135. M.L. Capece, R. Lydic, Amer. J. Physiol.- Regul. Integr. C., 42, 1430 - 1440 (1997), "cAMP and Protein Kinase A Modulate Cholinergic Rapid Eye Movement Sleep Generation""
  • 136. J.D. Krass, B. Jastorff, H.-G. Genieser, Anal. Chem., 69, 2575 - 2581 (1997), "Determination of Lipophilicity by Gradient Elution High-Performance Liquid Chromatography""
  • 137. C.S. Harmon, T.D. Nevins, Br. J. Dermatol., 136, 853 - 858 (1997), "Evidence that Activation of Protein Kinase A Inhibits Human Hair Follicle Growth and Hair Fibre Production in Organ Culture and DNA Synthesis in Human and Mouse Hair Follicle Organ Culture""
  • 138. G.A. Soff, T.L. Cornwell, D.L. Cundiff, S. Gately, T.M. Lincoln, J. Clin. Invest., 100, 2580 - 2587 (1997), "Smooth Muscle Cell Expression of Type I Cyclic GMP-Dependent Protein Kinase is Suppressed by Continuous Exposure to Nitrovasodilators, Theophylline, Cyclic GMP, and Cyclic AMP""
  • 139. J. Constantin, F. Suzuki-Kemmelmeier, N.S. Yamamoto, A. Bracht, Biochem. Pharmacol., 54, 1115 - 1125 (1997), "Production, Uptake, and Metabolic Effects of Cyclic AMP in the Bivascularly Perfused Rat Liver""
  • 140. E. Nishio, Y. Watanabe, Eur. J. Pharmacol., 339, 245 - 251 (1997), "Nitric Oxide Donor-Induced Apoptosis in Smooth Muscle Cells is Modulated by Protein Kinase C and Protein Kinase A""
  • 141. M. Yamamoto, N. Sato, H. Tajima, K. Furuke, A. Ohira, Y. Honda, J. Yodoi, Exp. Eye Res., 65, 645 - 652 (1997), "Induction of Human Thioredoxin in Cultured Human Retinal Pigment Epithelial Cells Through Cyclic AMP-Dependent Pathway - Involvement in the Cytoprotective Activity of Prostaglandin E-1""
  • 142. A.T. Grazul-Bilska, L.P. Reynolds, J.D. Kirsch, D.A. Redmer, Biol. Reprod., 54, 538 - 545 (1996), "Gap Junctional Intercellular Communication of Bovine Luteal Cells from Several Stages of the Estrous Cycle: Effects of Cyclic Adenosine 3\', 5\'- monophosphate""
  • 143. W.F. Jackson, Pharmacology, 52, 226 - 234 (1996), "Rp Diastereomeric Analogs of cAMP Inhibit Both cAMP-and cGMP-Induced Dilation of Hamster Mesenteric Small Arteries""
  • 144. I. Holen, P.B. Gordon, P.E. Stroemhaug, P.O. Seglen, Eur. J. Biochem., 236, 163 - 170 (1996), "Role of cAMP in the Regulation of Hepatocytic Autophagy""
  • 145. A. Hichami, E. Boichot, N. Germain, O. Coqueret, V. Lagente, Life Sci., 59, 255 - 261 (1996), "Interactions Between cAMP- and cGMP-dependent Protein Kinase Inhibitors and Phosphodiesterase IV Inhibitors on Arachidonate Release from Human Monocytes""
  • 146. H. Suzuki, I. Nakamura, N. Takahashi, T. Ikuhara, K. Matsuzaki, Y. Isogai, M. Hori, T. Suda, Endocrinology, 137, 4685 - 4690 (1996), "Calcitonin-induced Changes in the Cytoskeleton are Mediated by a Signal Pathway Associated with Protein Kinase A in Osteoclasts""
  • 147. A.V. Sirotkin, A.V. Makarevic, H.-G. Genieser, 3rd Intl. Conf. Cyclic Nucleotide Phosphodiesterases ( From Genes to Therapies ) Scotland, 0, 0 - 0 (1996), "The Effect of PDE Inhibitors and Other Regulators of PKA on the Secretory Activity of Porcine Ovarian Granulosa Cells""
  • 148. G. Pilar, D.B. Gray, S.D. Meriney, Life Sci., 58, 1979 - 1986 (1996), "Membrane Delimited and Intracellular Soluble Pathways in the Somatostatin Modulation of ACH Release""
  • 149. C. Kroner, I. Boekhoff, S.M. Lohmann, H.-G. Genieser, H. Breer, Eur. J. Biochem., 236, 632 - 637 (1996), "Regulation of Olfactory Signalling Via cGMP-dependent Protein Kinase""
  • 150. S. Nicolai, J. Willems, A. Zwijsen, E. Van Mechelen, H. Slegers, Free Radical Biol. Med., 21, 481 - 486 (1996), "Cyclic AMP-induced Differentiation Increases the Synthesis of Extracellular Superoxide Dismutase in Rat C6 Glioma""
  • 151. Z.Q. Li, S. Mardh, BBA-Mol. Cell Res., 1311, 133 - 142 (1996), "Interactions Between Ca2+ and cAMP-dependent Stimulatory Pathways in Parietal Cells""
  • 152. G. Tigyi, D.J. Fischer, A. Sebök, F. Marshall, D.L. Dyer, R. Miledi, J. Neurochem., 66, 549 - 558 (1996), "Lysophosphatidic Acid-Induced Neurite Retraction in PC12 Cells: Neurite-Protective Effects of Cyclic AMP Signaling""
  • 153. A. Hichami, E. Boichot, N. Germain, E. Berdyshev, O. Coqueret, V. Lagente, Mediat. Inflamm., 5, 425 - 428 (1996), "Phosphodiesterase 4 Inhibitors and DB-cAMP Inhibit TNF-Alpha Release From Human Mononuclear Cells - Effects of cAMP and cGMP-Dependent Protein Kinase Inhibitors""
  • 154. Y. Shimizu, D. Kielar, Y. Minokoshi, T. Shimazu, Biochem. J., 314, 485 - 490 (1996), "Noradrenaline Increases Glucose Transport Into Brown Adipocytes in Culture by a Mechanism Different from that of Insulin""
  • 155. I. Herrero, J. Sanchez-Prieto, J. Biol. Chem., 271, 30554 - 30560 (1996), "cAMP-Dependent Facilitation of Glutamate Release by Beta-Adrenergic Receptors in Cerebrocortical Nerve Terminals""
  • 156. U. Ikeda, M. Ikeda, S. Kano, T. Kanbe, K. Shimada, Eur. J. Pharmacol., 314, 197 - 202 (1996), "Effect of Cilostazol, a cAMP Phosphodiesterase Inhibitor, on Nitric Oxide Production by Vascular Smooth Muscle Cells""
  • 157. M. Quinonez, P.J. Romero, L. Rojas, Brain Res., 737, 327 - 330 (1996), "Action of Protein Kinase A Activators on the Caudal Neuromuscular Junction of Toad Tadpoles, Recorded on Synaptic Spots""
  • 158. E. Butt, U. Walter, in \""Platelets: A Practical Approach\"" IRL Press Oxford, 0, 259 - 278 (1996), "Cyclic Nucleotides: Measurement and Function""
  • 159. J. van Rijn, J. van den Berg, Int. J. Radiat. Oncol. Biol. Phys., 35, 313 - 319 (1996), "Effect of Adenosine 3\':5\'- Cyclic Monophosphate and Inhibition of Protein Kinase A on Heat Sensitivity in H35 Hepatoma Cells""
  • 160. F.-C. Liu, A.M. Graybiel, Neuron, 17, 1133 - 1144 (1996), "Spatiotemperal Dynamics of CREB Phosphorylation: Transient Versus Sustained Phosphorylation in the Developing Striatum""
  • 161. M.G. Aluigi, T. Cai, S. Gentleman, P. Wong, A. Albini, D.M. Noonan, G. Fassina, Fundam. and Clin. Immunology \'Apoptosis 1996\' edited by G. Bonnelli and F. M. Baccino, 4, 23 - 25 (1996), "Induction of Differentiation and Apoptosis in Retinoblastoma Cells by cAMP Analogs and Laminin""
  • 162. K. Anciaux, D. Roymans, H. Slegers, Arch. Physiol. Biochem., 104, 32 - 0 (1996), "Effect of cAMP- and cGMP-Analogues on the Enzymatic Activity of the Nucleoside Diphosphate Kinase of Rat C6 Glioma""
  • 163. A.V. Sirotkin, A.V. Makarevich, H.-G. Genieser, J. Physiol. Pharmacol., 47, 134 - 0 (1996), "Effect of Regulators of Protein Kinase A on IGF-I and Steroid Secretion by Porcine Granulosa Cells in Vitro""
  • 164. F. Takemoto, S. Uchida, H. Katagiri, Y. Oka, A. Nakao, K. Kurokawa, Am. J. Physiol., 37, 385 - 390 (1995), "Desensitization of Endothelin-1 Binding by Vasopressin Via a cAMP-mediated Pathway in Rat CCD""
  • 165. M. Gianni, M.L. Calzi, M. Terao, A. Rambaldi, E. Garattini, Biochem. Biophys. Res. Commun., 208, 846 - 854 (1995), "Tyrosine kinases but not cAMP dependent Protein Kinase Mediate the Induction of Leukocyte Alkaline Phosphatase by Granulocyte Colony stimulating Factor and Retinoic Acid in Acute Promyelocytic Leukemia Cells""
  • 166. M.L. Roy, H. Sontheimer, J. Neurochem., 64, 1576 - 1584 (1995), "ß-Adrenergic Modulation of Glial Inwardly Rectifying Potassium Channels""
  • 167. M. Bidri, P.-A. Becherel, L. Le Goff, L. Pieroni, J.-J. Guillosson, P. Debre, M. Arock, Biochem. Biophys. Res. Commun., 210, 507 - 517 (1995), "Involvement of Cyclic Nucleotides in the Immunomodulatory Effects of Nitric Oxide on Murine Mast Cells""
  • 168. S.A. Prestwich, H. Miyazaki, T.B. Bolton, Br. J. Pharmacol., 115, 147 - 157 (1995), "Effects of GTP gamma S on Muscarinic Receptor-stimulated Inositol Phospholipid Hydrolysis in Permeabilized Smooth Muscle From the Small Intestine""
  • 169. J.S. Sidhu, C.J. Omiecinski, J. Biol. Chem., 270, 12762 - 12773 (1995), "cAMP-associated Inhibition of Phenobarbital-inducible Cytochrome P450 Gene Expression in Primary Rat Hepatocyte Cultures""
  • 170. A.O.L. Wong, B.C. Moor, C.E. Hawkins, N. Narayanan, J. Kraicer, Neuroendocrinol., 61, 590 - 600 (1995), "Cytosolic Protein Kinase A Mediates the Growth Hormone (GH)-releasing Action of GH-releasing Factor in Purified Rat Somatotrophs""
  • 171. V. Reale, C.N. Hales, M.L.J. Ashford, J. Membr. Biol., 145, 267 - 278 (1995), "Regulation of Calcium-activated Nonselective Cation Channel Activity by Cyclic Nucleotides in the Rat Insulinoma Cell Line, CRI-G1""
  • 172. F. Mentz, M.D. Mossalayi, F. Ouaaz, P. Debre, Eur. J. Immunol., 25, 1798 - 1801 (1995), "Involvement of cAMP in CD3 T Cell Receptor Complex- and CD2-mediated Apoptosis of Human Thymocytes""
  • 173. F. Rodriguez-Pascual, M.T. Miras-Portugal, M. Torres, Neuroscience, 67, 149 - 157 (1995), "Cyclic GMP-dependent Protein Kinase Activation Mediates Inhibition of Catecholamines Secretion and Ca 2+ Influx in Bovine Chromaffin Cells""
  • 174. T. Barry, F. Delamere, E. Holland, I. Pavord, A. Knox, J. Appl. Physiol., 78, 623 - 28 (1995), "Production of PGE(2) by Bovine Cultured Airway Smooth Muscle Cells - Regulation by cAMP""
  • 175. O.K. Vintermyr, R. Böe, O.T. Brustugun, E. Maronde, A. Aakvaag, S.O. Doeskeland, Endocrinology, 136, 2513 - 2520 (1995), "Cyclic Adenosine Monophosphate (cAMP) Analogs 8-Cl- and 8-NH(2)-cAMP Induce Cell Death Independently of cAMP Kinase-Mediated Inhibition of the G(1)/S Transition in Mammary Carcinoma Cells (MCF-7)""
  • 176. J. Kano, T. Sugimoto, M. Fukase, K. Chihara, Biochem. Biophys. Res. Commun., 199, 271 - 276 (1994), "Direct Involvement of cAMP-Dependent Protein Kinase in the Regulation of Alkaline Phosphatase Activity by Parathyroid Hormone (PTH) and PTH-Related Peptide in Osteoblastic Umr-106 Cells""
  • 177. D.J. Church, V. van der Bent, M.B. Vallotton, A.M. Capponi, U. Lang, Am. J. Physiol., 266, 403 - 409 (1994), "Calcium Influx in Platelet Activating Factor- Induced Atrial Natriuretic Peptide Release in Rat Cardiomyocytes""
  • 178. Y. Konda, I. Gantz, J. Del Valle, Y. Shimoto, H. Miwa, T. Yamada, J. Biol. Chem., 269, 13162 - 13166 (1994), "Interaction of Dual Intracellular Signaling Pathways Activated by the Melanocortin-3 Receptor""
  • 179. A. Kaipia, T-.L. Penttila, J. Toppari, Eur. J. Endocrinol., 131, 323 - 329 (1994), "Follicle-stimulating Hormone Regulation of Inhibin Alpha-subunit mRNA in Staged Rat Semineferous Tubules""
  • 180. M. Ishikawa, Y. Ouchi, S.Z. Han, M. Akishita, K. Kozaki, K. Toba, A. Namiki, T. Yamaguchi, H. Orimo, Eur. J. Pharmacol., 269, 311 - 317 (1994), "Parathyroid Hormone-related Protein Reduces Cytosolic Free Ca 2+ Level and Tension in Rat Aortic Smooth Muscle""
  • 181. W.W. Li, S. Luan, S.L. Schreiber, S.M. Assmann, Plant Physiol., 106, 957 - 961 (1994), "Cyclic AMP Stimulates K+ Channel Activity in Mesophyll Cells of Vicia faba L.""
  • 182. J.R. Raymond, C.L. Olsen, Biochemistry, 33, 11264 - 11269 (1994), "Protein Kinase A Induces Phosphorylation of the Human 5-HT(1A) Receptor and Augments its Desensitization by Protein Kinase C in CHO-K1 Cells""
  • 183. V. Papadopoulos, P. Guarneri, Glia, 10, 75 - 78 (1994), "Regulation of C6 Glioma Cell Steroidogenesis by Adenosine 3\', 5\'- cyclic Monophosphate""
  • 184. O.G. Björnsson, J.D. Sparks, C.E. Sparks, G.F. Gibbons, Eur. J. Clin. Invest., 24, 137 - 148 (1994), "Regulation of VLDL Secretion in Primary Culture of Rat Hepatocytes: Involvement of cAMP and cAMP-dependent Protein Kinases""
  • 185. C. Schultz, M. Vajanaphanich, H.-G. Genieser, B. Jastorff, K.E. Barrett, R.Y. Tsien, Mol. Pharmacol., 46, 702 - 708 (1994), "Membrane-permeant Derivatives of Cyclic AMP Optimized for High Potency, Prolonged Activity, or Rapid Reversibility""
  • 186. M. Klin, M. Smogorzewski, H. Khilnani, M. Michnowska, S.G. Massry, Amer. J. Physiol., 30, 754 - 763 (1994), "Mechanisms of PTH-Induced Rise in Cytosolic Calcium in Adult Rat Hepatocytes""
  • 187. R.B. Pilz, M. Berjis, S.D. Idriss, J.S. Scheele, M. Suhasini, L. Gao, I.E. Scheffler, G.R. Boss, J. Biol. Chem., 269, 32155 - 32161 (1994), "Isolation and Characterization of HL-60 Cells Resistant to Nitroprusside-Induced Differentiation""
  • 188. O.P. Sharma, J.A. Flores, D.A. Leong, J.D. Veldhuis, Endocrinology, 134, 1915 - 1923 (1994), "Cellular Basis for Follicle-Stimulating Hormone-Stimulated Calcium Signaling in Single Rat Sertoli Cells: Possible Dissociation from Effects of Adenosine 3\',5\'-Monophosphate""
  • 189. L. Yu, N.C. Schaad, D.C. Klein, J. Neurochem., 60, 1436 - 1443 (1993), "Calcium Potentiates Cyclic AMP Stimulation of Pineal Arylalkylamine N-Acetyltransferase""
  • 190. J.C. Rodriguez-Aguilera, F. Navarro, A. Arroyo, J.M. Villalba, P. Navas, J. Biol. Chem., 268, 26346 - 26349 (1993), "Transplasma Membrane Redox System of HL- 60 Cells is Controlled by cAMP""
  • 191. D. Pinsky, R. Nowygrod, S. Koga, D. Stern, M. Oz, H. Liao, S. Morris, J. Brett, R. Sciacca, M. Karakurum, M. Van Lookeren Campagne, J. Platt, J. Clin. Invest., 92, 2994 - 3002 (1993), "Restoration of the cAMP Second Messenger Pathway Enhances Cardiac Preservation for Transplantation in a Heterotopic Rat Model""
  • 192. R.D. Watson, W.E. Yeh, D.P. Muehleisen, C.J. Watson, W.E. Bollenbacher, Mol. Cell. Endocrinol., 92, 221 - 228 (1993), "Stimulation of Ecdysteroidogenesis by Small Prothoracicotropic Hormone: Role of Cyclic AMP""
  • 193. M.E. Reyland, Mol. Endocrinol., 7, 1021 - 1030 (1993), "Protein Kinase C is a Tonic Negative Regulator of Steroidogenesis and Steroid Hydroxylase Gene Expression in Y1 Adrenal Cells and Functions Independently of Protein Kinase A""
  • 194. M. Zorn, E. Maronde, B. Jastorff, C. Richter-Landsberg, Eur. J. Cell Biol., 60, 351 - 357 (1993), "Differential Effects of Two Structurally Related N6-substituted cAMP Analogues on C6 Glioma Cells""
  • 195. H. Kaji, T. Sugimoto, M. Kanatani, M. Fukase, Biochem. Biophys. Res. Commun., 182, 1356 - 1361 (1992), "The Activation of cAMP-Dependent Protein Kinase is Directly Linked to the Stimulation of Bone Resorption by Parathyroid Hormone""
  • 196. T. Furumichi, Y. Yamada, T. Suzuki, H. Furui, K. Yamauchi, H. Saito, Jpn. Heart J., 33, 373 - 382 (1992), "Adenosine 3\', 5\' - Cyclic Monophosphate Inhibits In Vitro Angiogenesis Induced by Endothelial Cell Growth Factor""
  • 197. J. Hartikka, M. Staufenbiel, H. Lübbert, J. Neurosci. Res., 32, 190 - 201 (1992), "Cyclic AMP, But Not Basic FGF, Increases the In Vitro Survival of Mesencephalic Dopaminergic Neurons and Protects Them From MPP+-Induced Degeneration""
  • 198. K. Nishio, T. Morikage, N. Kubota, T. Ohmori, Y. Takeda, Y. Fujiwara, K. Miki, K. Abe, N. Saijo, Jpn. J. Cancer Res., 83, 754 - 60 (1992), "Alteration of Type II Regulatory Subunit of cAMP-dependent Protein Kinase in Human Cisplatin-Resistant Cells as a Basis of Collateral Sensivity to 8-chloro-cAMP""
  • 199. B.S. Skalhegg, B.F. Landmark, S.O. Doeskeland, V. Hansson, T. Lea, T. Jahnsen, J. Biol. Chem., 267, 15707 - 15714 (1992), "Cyclic AMP-dependent Protein Kinase Type I Mediates the Inhibitory Effects of 3\', 5\'-Cyclic Adenosine Monophosphate on Cell Replication in Human T Lymphocytes""
  • 200. S.R. Adams, A.T. Harootunian, Y.J. Büchler, S.S. Taylor, R.Y. Tsien, Nature, 349, 694 - 697 (1991), "Fluorescence Ratio Imaging of Cyclic AMP in Single Cells""
  • 201. S.O. Doeskeland, R. Boe, T. Bruland, O.K. Vintermyr, B. Jastorff, M. Lanotte, Method. Surveys Biochem. & Anal., E. Reid et al. (eds.). Royal Society Chem. Cambridge UK , Redwood Press Ltd., 21, 103 - 114 (1991), "Criteria Used to Judge That a Cellular Response is Mediated by Cyclic AMP""
  • 202. J.E.B. Reusch, N. Begum, K.E. Sussman, B. Draznin, Endocrinology, 129, 3269 - 3273 (1991), "Regulation of GLUT-4 Phosphorylation by Intracellular Calcium in Adipocytes""
  • 203. M. Lanotte, J.B. Riviere, S. Hermouet, G. Houge, O.K. Vintermyr, B.T. Gjertsen, S.O. Doeskeland, J. Cell. Physiol., 146, 73 - 80 (1991), "Programmed Cell Death (Apoptosis) Is Induced Rapidly and With Positive Cooperativity by Activation of Cyclic Adenosine Monophosphate-Kinase I in a Myeloid Leukemia Cell Line""
  • 204. Y.S. Cho-Chung, T. Clair, G. Tortora, H. Yokozaki, Pharmacol. Ther., 50, 1 - 33 (1991), "Role of Site-selective cAMP Analogs in the Control and Reversal of Malignancy""
  • 205. F. Guadagni, G. Tortora, M. Roselli, T. Clair, Y.S. Cho-Chung, J. Schlom, J.W. Greiner, Int. J. Cancer, 48, 413 - 422 (1991), "Carcinoembryonic Antigen Regulation in Human Colorectal Tumor Cells by a Site-Selective Cyclic AMP Analog: A Comparison with Interferon-Gamma""
  • 206. M.M. Van Lookeren Campagne, F.V. Diaz, B. Jastorff, E. Winkler, H.-G. Genieser, R.W. Kessin, J. Biol. Chem., 265, 5847 - 5854 (1990), "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues""
  • 207. Y.-J. Hei, K.L. MacDonell, J.H. McNeill, J. Diamond, Mol. Pharmacol., 39, 233 - 238 (1990), "Lack of Correlation Between Activation of Cyclic AMP-Dependent Protein Kinase and Inhibition of Contraction of Rat Vas Deferens by Cyclic AMP Analogs""
  • 208. R.P. Newton, S.G. Salih, J.A. Khan, Cyclic Nucleotide Phosphodiesterases: Structure M.D. Houslay ed., Wiley Interscience Chichester UK, 17, 141 - 159 (1990), "Cyclic CMP-Specific Phosphodiesterase Activity""
  • 209. Y. Miyagi, S. Sasayama, H. Nakajima, M. Fujita, H. Asanoi, J. Cardiovasc. Pharmacol., 15, 138 - 143 (1990), "Comparative Hemodynamic Effects of Intravenous Dobutamine and Dibutyryl Cyclic AMP, a New Inotropic Agent, in Severe Congestive Heart Failure""
  • 210. M. Yanagida, E. Gohda, I. Yamamoto, Neurosci. Lett., 114, 323 - 328 (1990), "Dibutyrylcytidine 3´,5´-cyclic Monophosphate Stimulates Neurite Outgrowth in Rat Pheochromocytoma PC12""
  • 211. H. Nakajima, Y. Miyagi, M. Fujita, S. Sasayama, Intl. J. Cardiol., 25, 55 - 62 (1989), "Effects of DBcAMP on Exercise Capacity in Patients with and without Chronic Heart Failure""
  • 212. R.P. Newton, T.J. Walton, S.A. Basaif, A.M. Jenkins, A.G. Brenton, D. Ghosh, F.M. Harris, Org. Mass Spectrom., 24, 679 - 688 (1989), "Identification of Butyryl Derivatives of Cyclic Nucleotides by Positive Ion Fast Atom Bombardment Mass Spectrometry and Mass-analysed Ion Kinetic Energy Spectrometry""
  • 213. G. Tortora, P. Tagliaferri, T. Clair, O. Colamonici, L.M. Neckers, R.K. Robins, J.-S. Cho-Chung, Blood, 71, 230 - 233 (1988), "Site-selective Cyclic AMP Analogs at Micromolar Concentrations Induce Growth Arrest and Differentiation of Acute Promyelocytic, Chronic Myelocytic, and Acute Lymphocytic Human Leukemia Cell Lines""
  • 214. P. Tagliaferri, G.R. Revankar, G.W. Crabtree, R.K. Robins, Y.S. Cho-Chung, D. Katsaros, T. Clair, S. Ally, G. Tortora, L.M. Neckers, B. Rubalcava, Z. Parandoosh, Y.-A. Chang, Cancer Res., 48, 1642 - 1650 (1988), "Synergistic Inhibition of Growth of Breast and Colon Human Cancer Cell Lines by Site-selective Cyclic AMP Analogs""
  • 215. Y. Furukawa, Y. Ogiwara, K. Saegusa, M. Takeda, S. Chiba, Jpn. Heart J., 29, 465 - 473 (1988), "Cardiovascular Effects of Dibutyryl Cyclic AMP in the Intact Dog Heart and the Isolated Cross-perfused Right Atrium""
  • 216. C. Richter-Landsberg, B. Jastorff, NATO ASI Ser. (Glial- Neur. Commun. Dev. Regener.), 2, 339 - 354 (1987), "Effect of Nerve Growth Factor and cAMP Analogs on Neuronal Differentiation in PC12 Cells: Studies with an Inhibitor of cAMP- Dependent Protein Kinases""
  • 217. D. Katsaros, G. Tortora, P. Tagliaferri, T. Clair, S. Ally, L.M. Neckers, R.K. Robins, Y.S. Cho-Chung, FEBS Lett., 223, 97 - 103 (1987), "Site-selective Cyclic AMP Analogs Provide a New Approach in the Control of Cancer Cell Growth""
  • 218. T. Clair, S. Ally, P. Tagliaferri, R.K. Robins, Y.S. Cho-Chung, FEBS Lett., 224, 377 - 384 (1987), "Site-selective Cyclic AMP Analogs Induce Nuclear Translocation of the RII cAMP Receptor Protein in Ha-MuSV-Transformed NIH/3T3 Cells""
  • 219. J.P. Gilbard, D.A. Dartt, Eur. Pat. Appl. EP 234854 A2 Appl. 87/301403 US Appl. 830997, 27, 0 - 0 (1987), "Preparations For Stimulation of Tear Secretion With Phosphodiesterase Inhibitors and Cyclic Nucleotide Analogues""
  • 220. E. Sato, S.S. Koide, Endocrine Research, 13, 399 - 405 (1987), "Follicular fluid constituents influencing spontaneous maturation of cultured mouse Oocytes""
  • 221. C. Erneux, J. Van Sande, B. Jastorff, J.E. Dumont, Biochem. J., 234, 193 - 197 (1986), "Modulation of Cyclic AMP Action in the Dog Thyroid by its Agonist and Antagonist Sp-and Rp- Adenosine-3\',5\'-Monophosphorothioate""
  • 222. C. Richter-Landsberg, B. Jastorff, J. Cell. Biol., 102, 821 - 829 (1986), "The Role of cAMP in Nerve Growth Factor-Promoted Neurite Outgrowth in PC12 Cells""
  • 223. C. Brandt, B. Jastorff, A. Hildebrandt, Roux\'s Arch. Dev. Biol., 195, 276 - 280 (1986), "Sporulation Delay by Stable cAMP Analogs in the Slime Mould Physarum Polycephalum""
  • 224. S.J. Scheinman, W.J. Stec, R. Coulson, Miner. Electrolyte Metab., 11, 85 - 90 (1985), "Effects of (Sp)- and (Rp)-Adenosine Cyclic 3\',5\' Phosphorothioates on Electrolyte Excretion by the Isolated Perfused Rat Kidney""
  • 225. T. Braumann, B. Jastorff, J. Chromatogr., 350, 105 - 118 (1985), "Physicochemical Characterization of Cyclic Nucleotides by Reversed Phase High-Performance Liquid Chromatography. II. Quantitative Determination of Hydrophobicity""
  • 226. M. Nakazawa, K. Takeda, Y. Nakagawa, H. Tamatsu, K. Matsui, H. Nakahara, T. Kimura, T. Kawada, S. Imai, J. Cardiovasc. Pharmacol., 7, 862 - 868 (1985), "In Vivo and In Vitro Assessment of the Cardiovascular Effects of 8-(Benzylthio)-N(6)-n-Butyl-Cyclic AMP""
  • 227. S. Matsui, E. Murakami, N. Takekoshi, J. Emoto, M. Matoba, Amer. J. Cardiol., 51, 1364 - 1368 (1983), "Hemodynamic Effects of Dibutyryl Cyclic AMP in Congestive Heart Failure""
  • 228. J.L. Ram, D. Gole, U. Shukla, L. Greenberg, J. Neurobiol., 14, 113 - 121 (1983), "Serotonin-activated Adenylate Cyclase and the Possible Role of Cyclic AMP in Modulation of Buccal Muscle Contraction in Aplysia""
  • 229. V.L. Schaeffer, A.N. Masoud, R.J. Rubin, J. Pharm. Sci., 72, 1255 - 1259 (1983), "Analysis of Monobutyryl and Dibutyryl Derivates of Adenosine 3´,5´-Monophosphate in Biological Samples Using Isocratic Ion Pair High-Performance Liqiud Chromatography""
  • 230. H. Kitaoka, K. Ohya, J. Chromatogr., 238, 495 - 499 (1982), "Determination of sodium N6 , O2\'- dibutyryladenosine cyclic 3\', 5\' - (hydrogenphosphate) and its Hydrolysis Products by High-performance Liquid Chromatography""
  • 231. A.M. Gronenborn, G.M. Clore, Biochemistry, 21, 4040 - 4048 (1982), "Proton Nuclear Magnetic Resonance Studies on Cyclic Nucleotide Binding to the Escherichia coli Adenosine Cyclic 3\',5\'- Phosphate Receptor Protein""
  • 232. B. Jastorff, in: \""Cell Regulation by Intracellular Signal Molecules\"" St. Swillens ed. 195 - 207 Plenum Press New York London, 0, 0 - 0 (1982), "The Effects of cyclic Nucleotide Derivatives on Cell Metabolism""
  • 233. Z.Y. Friedman, M. Lowe, Z. Selinger, Biochim. Biophys. Acta, 675, 40 - 45 (1981), "Beta-Adrenergic Receptor Stimulated Peroxidase Secretion from Rat Lacrimal Gland""
  • 234. J.C. Foreman, L.M. Lichtenstein, Biochim. Biophys. Acta, 629, 587 - 603 (1980), "Induction of Histamine Secretion by Polycations""
  • 235. P. Robberecht, M. Deschodt-Lanckman, M.-C. Woussen-Colle, P. De Neef, J.C. Camus, J. Christophe, Mol. Pharmacol., 17, 268 - 274 (1980), "Butyryl Derivatives of Cyclic GMP Interfere With the Biological and the Immunological Properties of the Pancreozymin-Gastrin Family of Peptides""
  • 236. S.R. Rannels, J.D. Corbin, J. Biol. Chem., 255, 7085 - 7088 (1980), "Two Different Intrachain cAMP Binding Sites of cAMP-Dependent Protein Kinases""
  • 237. S.H Francis, T.M. Lincoln, J.D. Corbin, J. Biol. Chem., 255, 620 - 626 (1980), "Characterization of a Novel cGMP Binding Protein from Rat Lung""
  • 238. R.M. Niles, K.W. Ludwig, J.S. Makarski, J. Natl. Cancer Inst., 63, 909 - 911 (1979), "Differential Growth Inhibition in Two Human Carcinoma Cell Lines by Cyclic Adenosine 5\'-Monophosphate Analogs""
  • 239. S.R. Peikin, C.L. Costenbader, J.D. Gardner, J. Biol. Chem., 254, 5321 - 5327 (1979), "Actions of Derivatives of Cyclic Nucleotides on Dispersed Acini from Guinea Pig Pancreas - Discovery of a Competitive Antagonist of the Action of Cholecystokinin""
  • 240. K. Nishikori, H. Maeno, J. Biol. Chem., 254, 6099 - 6109 (1979), "Close Relationship between Adenosine 3\',5\'-Monophosphate-dependent Endogenous Phosphorylation of a Specific Protein and Stimulation of Calcium Uptake in Rat Uterine Microsomes""
  • 241. F. Eckstein, Accounts of Chemical Research, 12, 204 - 210 (1979), "Phosphorothioate analogues of nucleotides""
  • 242. D. Yee, W.W. Armstrong, F. Eckstein, Biochemistry, 18, 4116 - 4120 (1979), "Mechanistic Studies on Deoxyribonucleic Acid Dependent Ribonucleic Acid Polymerase from Escherichia coli Using Phosphorothioate Analogues. 1. Initiation and Pyrophosphate Exchange Reactions""
  • 243. F. Eckstein, J.C. Foreman, FEBS Lett., 91, 182 - 185 (1978), "Actions of Adenosine and Guanosine 3\', 5\' Cyclic Phosphorothioates on Histamine Secretion""
  • 244. G.A.M. Breen, J.F. McGinnis, J. de Vellis, J. Biol. Chem., 253, 2554 - 2562 (1978), "Modulation of the Hydrocortisone Induction of Glycerol Phosphate Dehydrogenase by N6,O2\'-Dibutyryl Cyclic AMP, Norepinephrine, and Isobutylmethylxanthine in Rat Brain Cell Cultures""
  • 245. A. Narimatsu, N. Taira, Eur. J. Pharmacol., 42, 71 - 78 (1977), "Positive Dromotropic Effect of Dibutyryl Cyclic Adenosine 3\',5\'-Monophosphate on the Atrioventricular Node""
  • 246. J.P. O\'Neill, A.P. Li, A.W. Hsie, BBA, 497, 35 - 45 (1977), "Action of Cyclic Nucleotide Analogues in Chinese Hamster Ovary Cells""
  • 247. W.G. Nayler, Adv. Drug Res., 12, 39 - 51 (1977), "Cyclic Nucleotides and the Heart""
  • 248. F. Eckstein, S. Eimerl, M. Schramm, FEBS Lett., 64, 92 - 94 (1976), "Adenosine 3\', 5\' Cyclic Phosphorothioate: An Effective Inducer of Amylase Secretion in Rat Parotid Slices""
  • 249. M.M. Bevers, J. van Rijn, R. van Wijk, FEBS Letters, 72, 275 - 278 (1976), "A Comparative Study on the Metabolism of N6, O2\'-Dibutyryl Adenosine 3\', 5\'-Monophosphate in Various Rat Hepatoma Cell Lines in Culture""
  • 250. D.B. Evans, C.S. Parham, M.T. Schenck, R.J. Laffan, J. Cyclic Nucleotide Res., 2, 307 - 319 (1976), "Stimulation of Myocardial Contractility by a New Cyclic Nucleotide Analog, 8-(Benzylthio)-N6-n-butyladenosine Cyclic 3\', 5\'- Phosphate (SQ 80122)""
  • 251. J.P. O\'Neill, C.H. Schröder, A.W. Hsie, J. Biol. Chem., 250, 990 - 995 (1975), "Hydrolysis of Butyryl Derivatives of Adenosine Cyclic 3\',5\'-Monophosphate by Chinese Hamster Ovary Cell Extracts and Characterization of the Products""
  • 252. J.P. Miller, A.H. Beck, L.N. Simon, R.B. Meyer, J. Biol. Chem., 250, 426 - 431 (1975), "Induction of Hepatic Tyrosine Aminotransferase in Vivo by Derivatives of Cyclic Adenosine 3\',5\'- Monophosphate""
  • 253. G.R. Siggins, S.J. Henriksen, Science, 189, 559 - 560 (1975), "Analogs of Cyclic Adenosine Monophosphate: Correlation of Inhibition of Purkinje Neurons with Protein Kinase Activation""
  • 254. H. Nozaki, A. Okuaki, Tohoku J. Exp. Med., 115, 145 - 154 (1975), "Responses to Exogenous Dibutyryl Adenosine 3\',5\'- Monophosphate of Cardiac Output and Blood Flow in the Renal, Superior Mesenteric and Carotid Arteries in Anesthetized Dogs""
  • 255. R.B. Meyer, J.P. Miller, Life Sci., 14, 1019 - 1040 (1974), "Analogs of Cyclic AMP and Cyclic GMP: General Methods of Synthesis and the Relationship of Structure to Enzymatic Activity""
  • 256. M.L. Karlinsky, D.S. Sager, N.A. Kurtzman, V.K.G. Pillay, Amer. J. Physiol., 227, 1226 - 1231 (1974), "Effect of Parathormone and Cyclic Adenosine Monophosphate on Renal Bicarbonate Reabsorption""
  • 257. S. Imai, T. Otorii, K. Takeda, Y. Katano, D. Horii, Jpn. J. Pharmacol., 24, 499 - 510 (1974), "Effects of Cyclic AMP and Dibutyryl Cyclic AMP on the Heart and Coronary Circulation""
  • 258. R.S. Antonoff, J.J. Ferguson, J. Biol. Chem., 249, 3319 - 3321 (1974), "Photoaffinity Labeling with Cyclic Nucleotides""
  • 259. T. Posternak, G. Weimann, Meth. Enzymol., 38, 399 - 409 (1974), "[54] The Preparation of Acylated Derivatives of Cyclic Nucleotides""
  • 260. M. Nelböck, G. Michal, G. Weimann, Pure Appl. Chem., 35, 411 - 437 (1973), "Analogues of Cyclic AMP and their Physiological Response""
  • 261. J.P. Miller, D.A. Shuman, M.B. Scholten, M.K. Dimmitt, C.M. Stewart, T.A. Khwaja, R.K. Robins, L.N. Simon, Biochemistry, 12, 1010 - 1016 (1973), "Synthesis and Biological Activity of Some 2\' Derivatives of Adenosin 3\',5\' - Cyclic Phosphate""
  • 262. C.E. Guthrow, H. Rasmussen, D.J. Brunswick, B.S. Cooperman, Proc. Natl. Acad. Sci. USA, 70, 3344 - 3346 (1973), "Specific Photoaffinity Labeling of the Adenosine 3\': 5\'- Cyclic Monophosphate Receptor in Intact Ghosts from Human Erythrocytes""
  • 263. M. Szabo, G. Burke, Biochim. Biophys. Acta, 264, 289 - 299 (1972), "Uptake and Metabolism of 3\',5\'- Cyclic Adenosine Monophosphate and N6, O2\'-Dibutyryl 3\',5\'- Cyclic Adenosine Monophosphate in Isolated Bovine Thyroid Cells""
  • 264. E. Kaukel, K. Mundhenk, H. Hilz, Eur. J. Biochem., 27, 197 - 200 (1972), "N6-Monobutyryladenosine 3\': 5\'- Monophosphate as the Biologically Active Derivative of Dibutyryladenosine 3\': 5\'- Monophosphate in HeLa S3 Cells""
  • 265. W.B. Anderson, R.L. Perlman, I. Pastan, J. Biol. Chem., 247, 2717 - 2722 (1972), "Effect of Adenosine 3\', 5\'- Monophosphate Analogues on the Activity of the Cyclic Adenosine 3\', 5\'- Monophosphate Receptor in Escherichia coli""
  • 266. K.N. Prasad, Proc. Soc. Exp. Biol. Med., 140, 126 - 129 (1972), "Neuroblastoma Clones: Prostaglandin Versus Dibutyryl Cyclic AMP, 8-Benzylthio-Cyclic AMP, Phosphodiesterase Inhibitors and X-rays""
  • 267. A.L. Steiner, C.W. Parker, D.M. Kipnis, J. Biol. Chem., 247, 1106 - 1113 (1972), "Radioimmunoassay for Cyclic Nucleotides. I. Preparation of Antibodies and Iodinated Cyclic Nucleotides""
  • 268. L. Szaduykis-Szadurski, G. Weimann, F. Berti, Pharmacol. Res. Commun., 4, 63 - 69 (1972), "Pharmacological Effects of Cyclic Nucleotides and their Derivatives on Tracheal Smooth Muscle""
  • 269. R.J. Bauer, K.R. Swiatek, R.K. Robins, L.N. Simon, Biochem. Biophys. Res. Commun., 45, 526 - 531 (1971), "Adenosine 3\',5\'- cyclic Monophosphate Derivatives II. Biological Activity of Some 8-Substituted Analogs""
  • 270. J.-P. Jost, H.V. Rickenberg, Annu. Rev. Biochem., 40, 741 - 774 (1971), "Cyclic AMP""
  • 271. M. Du Plooy, G. Michal, G. Weimann, M. Nelboeck, R. Paoletti, Biochim. Biophys. Acta, 230, 30 - 39 (1971), "Cyclophosphates I. Effect of Various Cyclophosphates on Phosphorylase b Kinase Activation""
  • 272. G.I. Drummond, D.L. Severson, Ann. Rep. Med. Chem., 1, 215 - 226 (1971), "Biological Actions of Cyclic AMP Analogs""
  • 273. M. Blecher, J.T. Ro\'Ane, P.D. Flynn, Arch. Biochem. Biophys., 142, 351 - 362 (1971), "Biological Roles for 3\',5\'- Cyclic Nucleotides. I. Lipolytic Agents in isolated Rat Epididymal Adipose Cells and Substrates for Adipose Tissue Phosphodiesterase""
  • 274. C.A. Free, M. Chasin, V.S. Paik, S.M. Hess, Biochemistry, 10, 3785 - 3789 (1971), "Steroidogenic and Lipolytic Activities of 8-Substituted Derivatives of Cyclic 3\',5\'-Adenosine Monophosphate""
  • 275. T. Posternak, G. Cehovic, Ann. New York Acad. Sci., 185, 42 - 49 (1971), "Derivatives and Analogues of Cyclic Nucleotides""
  • 276. G. Michal, M. Nelböck, G. Weimann, Z. Anal. Chem., 252, 189 - 193 (1970), "Cyclophosphate III. Spaltung Verschiedener Cyclophosphate durch Phosphodiesterase aus Herz und Fettgewebe""
  • 277. M. Blecher, J.T. Ro\'Ane, P.D. Flynn, J. Biol. Chem., 245, 1867 - 1870 (1970), "Metabolism of Dibutyryl Cyclic Adenosine 3\', 5\'- Monophosphate During its Regulation of Lipolysis and Glucose Oxidation in Isolated Epididymal Adipocytes""
  • 278. R.A. Levine, Clin. Pharm. Therap., 11, 238 - 243 (1970), "Effects of Exogenous Adenosine 3\',5\'-monophosphate in Man""
  • 279. N.I. Swislocki, Anal. Biochem., 38, 260 - 269 (1970), "Decomposition of Dibutyryl Cyclic AMP in Aqueous Buffers""
  • 280. R.A. Levine, A. Washington, Endocrinology, 87, 377 - 382 (1970), "Glycogenolytic Activity of Cyclic 3\',5\'-Monophosphates in Perfused Rat Liver""
  • 281. G.I. Drummond, C.A. Powell, Mol. Pharmacol., 6, 24 - 30 (1970), "Analogues of Adenosine 3\', 5\'-Cyclic Phosphate as Activators of Phosphorylase b Kinase and as Substrates for Cyclic 3\', 5\'-Nucleotide Phosphodiesterase""
  • 282. W.F. Henion, E.W. Sutherland, T.H. Posternak, Biochim. Biophys. Acta, 148, 106 - 113 (1967), "Effects of Derivatives of Adenosine 3\', 5\'-Phosphate on Liver Slices and Intact Animals""
  • 283. J.-G. Falbriard, T. Posternak, E.W. Sutherland, BBA, 148, 99 - 105 (1967), "Preparation of Derivatives of Adenosine 3\', 5\'-Phosphate""
  • 284. T. Posternak, E.W. Sutherland, W.F. Henion, BBA, 65, 558 - 560 (1962), "Derivatives of Cyclic 3\',5\'- Adenosine Monophosphate""

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