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cAMP modified at the exocyclic oxygen
  1. axial (Sp-) (1)
  2. equatorial (Rp-) (3)
cGMP modified at the exocyclic oxygen
  1. equatorial (Rp-) (1)
Modifications
  1. 1-cAMP (6)
  2. 2-cAMP (5)
  3. 3-cAMP (4)
  4. 6-cAMP (5)
  5. 7-cAMP (1)
  6. 8-cAMP (9)
  7. 2'-cAMP (17)
  8. 3'-cAMP (5)
  9. 1-cGMP (1)
  10. 2-cGMP (5)
  11. 6-cGMP (3)
  12. 8-cGMP (5)
  13. 2'-cGMP (11)
  14. 5'-cAMP (2)
Lipophilicity

Lipophilicity ranking is based on log kw data. To be membrane-permeant, analogues should have a log kw of at least 1.2
See also: Lipophilic Ranking of Cyclic Nucleotide Analogs

  1. 0.00 - 1.00 (14)
  2. 1.00 - 2.00 (18)
  3. 2.00 - 3.00 (14)
  4. 3.00 - 4.00 (2)
Target
  1. Epac Activator (2)
  2. PKA (cAK) Activator (15)
  3. PKA (cAK) Inhibitor (2)
  4. PKG (cGK) Activator (5)

Special Task Cyclic Nucleotides

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2',3'-cAMP
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2',3'-cCMP
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2',3'-cGMP
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2',3'-cIMP
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2',3'-cUMP
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2'-AHC-cCMP
SEE DETAILS
2'-AHC-cUMP
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2'-C-Me-cAMP
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2'-dcAMP
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2'-dcGMP
SEE DETAILS
2'-F-dcAMP
SEE DETAILS
2'-Fluo-AHC-cAMP
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