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DT-3

PKG inhibitor peptide DT-3
Peptide-based inhibitor of protein kinase G
Cat. No.: D 052
    
CAS No.: 
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Product Name Price (net) Qty
Cat. No.: D 052-005
Unit: 0.5 mg / ~0.15 µmol
$165.00
Peptide-based inhibitor of protein kinase G type Iα and Iβ. Detailed technical information available. Reference: Dostmann et al., Proc. Natl. Acad. Sci. USA, 97, 14772 - 14777 (2000). Biolog also offers the control peptide W45 (Cat. No. W 001).
Cat. No. D 052
Purity > 95% HPLC
Salt form TFA
Storage temperature -20°C / -4°F
Molecular formula C₁₅₂H₂₅₉N₅₃O₂₇S₁
Molecular weight [g/mol] 3293,1
  • 1. Koika V., Zhou Z., Vasileidis I., Roussos C., Finetti F., Monti M., Morbidelli L.Papapetropoulos A., Vasc. Pharmacol., 53, 215 - 222 (2010), "PKG-I Inhibition Attenuates Vascular Endothelial Growth Factor-stimulated Angiogenesis"
  • 2. Lohmann S. M.Walter U., Frontiers Biosci., 10, 1313 - 1328 (2005), "Tracking Functions of cGMP-dependent Protein Kinase"
  • 3. Dostmann W. R. G., Tegge W., Frank R., Nickl C. K., Taylor M. S.Brayden J. E., Pharmacol. Ther., 93, 203 - 215 (2002), "Exploring the Mechanisms of Vascular Smooth Muscle Tone with Highly Specific, Membrane-permeable Inhibitors of Cyclic GMP-dependent Protein Kinase I Alpha"
  • 4. Dostmann W. R. G., Nickl C. K., Taylor M. S., Brayden J. E., Frank R.Ten Eyck L. F., Cell. Biol. Mol. Lett., 6, 458 - 458 (2001), "Highly Specific and Membrane Permeant Peptide Inhibitors of cGMP-Dependent Protein Kinase I alpha"
  • 5. Dostmann W. R. G., Taylor M. S., Nickl C. K., Brayden J. E., Frank R.Tegge W., Proc. Natl. Acad. Sci. U.S.A., 97, 14772 - 14777 (2000), "Highly Specific, Membrane-permeant Peptide Blockers of cGMP-dependent Protein Kinase I Alpha Inhibit NO-induced Cerebral Dilation"