Alternative structural projections:
Cyclic GMP analogue lacking purine N-7 nitrogen for receptor mapping studies. Detailed technical information and references available. References: Hebert et al., J. Biol. Chem., 273, 5557 - 5565 (1998); Quynh-Hoa et al., Angew. Chem., 94, 366 (1982).
| Cat. No. | D 099 |
| CAS number | [81611-03-2] |
| Purity | > 98% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₁H₁₂N₄O₇P · Na |
| Molecular weight [g/mol] | 366.2 |
| Modifications | 7-cGMP |
| Target | PKG (cGK) Activator |
| Absorption max [nm] | 260 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 10600 |
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- 2. Hebert M. C., Schwede F., Jastorff B.Cote R. H., J. Biol. Chem., 273, 5557 - 5565 (1998), "Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phoshodiesterase Using cGMP Analogs"
- 3. Couchie D., Petridis G., Jastorff B.Erneux C., Eur. J. Biochem., 136, 571 - 575 (1983), "Characterization of Phosphodiesterase Catalytic Sites by Means of Cyclic Nucleotide Derivatives"
- 4. Tran-Thi Q.-A., Franzen D.Seela F., Angew. Chem., 94, 366 - 366 (1982), "7-Desazaguanosin-3´,5´-Phosphat - ein isosteres cGMP-Analogon mit hoher Affinität zu Cyclonucleotid-Phosphodiesterase"
