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2'-O-MB-cCMP

2'- O- Monobutyrylcytidine- 3', 5'- cyclic monophosphate ( 2'-O-MB-cCMP ), sodium salt
Cat. No.: M 082
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: M 082-05
Unit: 5 µmol / ~2 mg
$218.00

For other salt forms please inquire. 2'-O-MB-cCMP is a precursor and biologically inactive analogue of the putative second messenger nucleotide cCMP (Cat. No. C 001). During metabolic activation by esterases both cCMP and butyrate are released. Detailed technical information available. Reference: Wolter et al., Naunyn Schmiedebergs Arch. Pharmacol., 387, 1163 - 1175 (2014).

Cat. No. M 082
CAS number [pending]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₃H₁₇N₃O₈P · Na
Molecular weight [g/mol] 397,3
Lipophilicity 1.51
Absorption max [nm] 270
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 9000
  • 1. Wolter S., Dove S., Golombek M., Schwede F.Seifert R., Naunyn-Schmiedeberg's Arch. Pharmacol., 387, 1163 - 1175 (2014), "N4-monobutyryl-cCMP Activates PKA RIalpha and PKA RIIalpha more Potently and with Higher Efficacy than PKG Ialpha in Vitro but not in Vivo"