The second messenger cyclic AMP immobilized on agarose by an aminohexyl spacer attached to position 6 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a shorter spacer (6-AE-cAMP-Agarose, Cat. No. A 111) and as a PDE-resistant version (Sp-6-AH-cAMPS-Agarose, Cat. No. A 108). Detailed technical information available. Reference: Poteet-Smith et al., J. Biol. Chem., 272, 379 - 388 (1997).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).
Cat. No. | A 036 |
CAS number | [pending] |
Appearance | Suspension in 30 mM Na₂HPO₄ buffer (pH 7) |
Storage temperature | 4°C / 39°F |
Modifications | 6-cAMP |