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Cl-ANT-ITP

2'- / 3'- O- (5- Chloroanthraniloyl)inosine- 5'- O- triphosphate ( Cl-ANT-ITP ), sodium salt
Cat. No.: C 132
    
CAS No.: [1350521-48-0]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: C 132-05
Unit: 5 µmol / ~3.3 mg
$315.00

For other salt forms please inquire. Analogue of inosine-5'-triphosphate with only moderate intrinsic fluorescence (λexc 350 nm; λem ~450 nm), increasing considerably within hydrophobic environment. Inhibitor of mammalian adenylate cyclases. Detailed technical information available. Reference: Geduhn et al., J. Pharmacol. Exp. Ther., 336, 104 - 115 (2011).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6.

Cat. No. C 132
CAS number [1350521-48-0]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Light-sensitive True
Molecular formula C₁₇H₁₉ClN₅O₁₅P₃ (free acid)
Molecular weight [g/mol] 661,7 (free acid)
Excitation max [nm] 350
Emission max [nm] 431
Absorption max [nm] 255
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14600
  • 1. Seifert R.Dove S., Pharmacol. Therapeut., 140, 200 - 212 (2013), "Inhibitors of Bacillus anthracis Edema Factor"
  • 2. Geduhn J., Dove S., Shen Y., Tang W.-J., König B.Seifert R., J. Pharmacol. Exp. Ther., 336, 104 - 115 (2011), "Bis-Halogen-Anthraniloyl-Substituted Nucleoside 5´-Triphosphate as Potent and Selective Inhibitors of Bordetella Pertussis Adenylyl Cyclase Toxin"