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Di-MANT-c-diGMP

2'-, 2''- O- (Di- N'- methylanthraniloyl)- cyclic diguanosine monophosphate ( Di-MANT-c-diGMP ), sodium salt
Fluorescent analogue of c-diGMP
Cat. No.: D 101
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: D 101-001
Unit: 0.1 µmol / ~0.1 mg
$293.00

For other salt forms please inquire. Membrane permeant, fluorescent analogue of the bacterial second messenger c-diGMP (Cat. No. C 057). The MANT fluorophore (λexc 355 nm; λem 448 nm) has a certain sensitivity for its environment and can change its spectral properties upon binding. Compare: Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983). Detailed technical information available. Reference: Abdul-Sater et al., Microbes Infect., 14, 188 - 197 (2012).

Cat. No. D 101
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₃₆H₃₈N₁₂O₁₆P₂ (free acid)
Molecular weight [g/mol] 956.7 (free acid)
Excitation max [nm] 355
Emission max [nm] 448
Absorption max [nm] 253
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 38700
UV pH value 8
  • 1. Abdul-Sater A. A., Grajkowski A., Erdjument-Bromage H., Plumlee C., Levi A., Schreiber M. T., Lee C., Shuman H., Beaucage S. L.Schindler C., Microbes Infect., 14, 188 - 197 (2012), "The Overlapping Host Reponses to Bacterial Cyclic Dinucleotides"
  • 2. Hiratsuka T., Biochim. Biophys. Acta, 742, 496 - 508 (1983), "New Ribose-modified Fluorescent Analogs of Adenine and Guanine Nucleotides Available as Substrates for Various Enzymes"