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c-di-2'-dGMP

2'- Deoxy- cyclic diguanosine monophosphate ( c-di-2'-dGMP / c-(2'-dGpGp) ), sodium salt
Analogue of c-diGMP
Cat. No.: D 145
    
CAS No.: [132182-18-4]
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Product Name Price (net) Qty
Cat. No.: D 145-001
Unit: 0.1 µmol / ~67 µg
$235.00
For other salt forms please inquire. c-di-2'-dGMP is an analogue of the bacterial second messenger c-diGMP (Cat. No. C 057) which can be useful in studies on ligand-receptor interactions. Detailed technical information available. References: Mano et al., ChemMedChem, 2, 1410 - 1413 (2007); Shanahan et al., J. Amer. Chem. Soc., 133, 15578 - 15592 (2011).
Cat. No. D 145
CAS number [132182-18-4]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₂₀H₂₄N₁₀O₁₃P₂ (free acid)
Molecular weight [g/mol] 674,4 (free acid)
Absorption max [nm] 254
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 23700
  • 1. Shanahan C. A., Gaffney B. L., Jones R. A.Strobel S. A., Biochemistry, 52, 365 - 377 (2013), "Identification of c-di-GMP Derivatives Resistant to an EAL Domain Phosphodiesterase"
  • 2. Shanahan C. A., Gaffney B. L., Jones R. A.Strobel S. A., J. Am. Chem. Soc., 133, 15578 - 15592 (2011), "Differential Analogue Binding by Two Classes of C-Di-GMP Riboswitches"
  • 3. Mano E., Hyodo M., Sato Y., Ishihara Y., Ohta M.Hayakawa Y., ChemMedChem, 2, 1410 - 1413 (2007), "Synthesis of Cyclic Bis(3'-5')-2'-deoxyguanylic/guanylic acid (c-dGpGp) and Its Biological Activities to Microbes"