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Alternative structural projections:

c[3'-Fluo-AHC-G(2',5')pA(3',5')p]

Cyclic (3'- O- (6- [fluoresceinyl]aminohexylcarbamoyl)guanosine- (2' −> 5')- monophosphate- adenosine- (3' −> 5')- monophosphate) ( c[3'-Fluo-AHC-G(2',5')pA(3',5')p] ), sodium salt
Cat. No.: C 194
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: C 194-001
Unit: 0.1 µmol / ~0.1 mg
$325.00

For other salt forms please inquire. Fluorescent analogue of the metazoan cyclic dinucleotide second messenger and STING activator c[G(2',5')pA(3',5')p] (aka cGAMP(2'-5') or 2'3'-cGAMP, Cat. No. C 161) with λexc 494 nm and λem 517 nm.

c[G(2',5')pA(3',5')p] was found to be the metazoan second messenger produced by the mammalian innate immune DNA sensor cGAMP synthase (cGAS). Detailed technical information available. References for c[G(2',5')pA(3',5')p]: Gao et al., Cell, 153, 1094 - 1107 (2013); Ablasser et al., Nature, 498, 380 - 384 (2013); Zhang et al., Mol. Cell, 51, 226 - 235 (2013); Diner et al., Cell Rep., 3, 1355 - 1361 (2013).

Cat. No. C 194
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₄₈H₄₈N₁₂O₂₀P₂
Molecular weight [g/mol] 1174.9
Excitation max [nm] 494
Emission max [nm] 517
Absorption max [nm] ~494
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] ~79000
UV pH value 9