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AMP-CP

Adenosine- 5'- O- (α, β- methylene)diphosphate ( AMP-CP / AMPCP / APCP / AOPCP ), sodium salt

Hydrolysis-resistant form of ADP
Cat. No.: A 070
    
CAS No.: [104835-70-3]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 070-05
Unit: 5 µmol / ~2.1 mg
$61.00

For other salt forms please inquire. Hydrolytically stable analogue of ADP and starting structure for synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Inhibitor of CD73. Detailed technical information available. References: Hoehn et al., J. Neurochem., 54, 256 - 265 (1990); Synnestvedt et al., J. Clin. Invest., 110, 993 - 1002 (2002).

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. A 070
CAS number [104835-70-3]
Purity > 95% HPLC
Salt form sodium salt
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Molecular formula C₁₁H₁₇N₅O₉P₂ (free acid)
Molecular weight [g/mol] 425.2(free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
  • 1. Song E.-K., Park H.-J., Kim J.-S., Lee H.-H., Kim U.-H.Han M.-K., J. Biochem. Biophys. Methods, 63, 161 - 169 (2005), "A Novel Fluorometric Assay for ADP-ribose Pyrophosphatase Activity"
  • 2. Synnestvedt K., Furuta G. T., Comerford K. M., Louis N., Karhausen J., Eltzschig H. K., Hansen K. R., Thompson L. F.Colgan S. P., J. Clin. Invest., 110, 993 - 1002 (2002), "Ecto-5'-Nucleotidase (CD73) Regulation by Hypoxia-Inducible Factor-1 Mediates Permeability Changes in Intestinal Epithelia"
  • 3. Picher M., Sevigny J., D'Orleans-Juste P.Beaudoin A. R., Biochem. Pharmacol., 51, 1453 - 1460 (1996), "Hydrolysis of P2-Purinoreceptor Agonists by a Purified Ectonucleotidase from the Bovine Aorta, the ATP-Diphosphohydrolase"
  • 4. Hoehn K.White T. D., J. Neurochem., 54, 256 - 265 (1990), "Role of Excitatory Amino Acid Receptors in K+- and Glutamate-Evoked Release of Endogenous Adenosine from Rat Cortical Slices"