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ADPRP

Adenosine- 5'- O- diphosphoribose phosphate ( ADPRP ), sodium salt
Cat. No.: A 190
    
CAS No.: [53595-18-9]
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Product Name Price (net) Qty
Cat. No.: A 190-05
Unit: 5 µmol / ~3.2 mg
$90.00
For other salt forms or higher purity please inquire. ADPRP is an analogue of adenosine-5'-O-diphosphoribose (ADP-ribose or ADPR) in which the ribose 2'-hydroxy group is phosphorylated; potential metabolite of NADP+ and β-NAADP (Cat. No. N 018). Detailed technical information available. References: Roitelman & Shechter, J. Lipid Res., 27, 828 - 835 (1986); Aarhus, R. et al., J. Biol. Chem., 270, 30327 - 30333 (1995);  Schmid et al., FEBS Lett., 585, 3544 - 3548 (2011).
Cat. No. A 190
CAS number [53595-18-9]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₅H₂₄N₅O₁₇P₃ (free acid)
Molecular weight [g/mol] 639,3 (free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
  • 1. Schmid F., Bruhn S., Weber K., Mittrücker H.-W.Guse A. H., FEBS Lett., 585, 3544 - 3548 (2011), "CD38: A NAADP Degrading Enzyme"
  • 2. Aarhus R., Graeff R. M., Dickey D. M., Walseth T. F.Lee H. C., J. Biol. Chem., 270, 30327 - 30333 (1995), "ADP-ribosyl Cyclase and CD38 Catalyze the Synthesis of a Calcium-mobilizing Metabolite from NADP+"
  • 3. Roitelman J.Shechter I., J. Lipid Res., 27, 828 - 835 (1986), "Allosteric and Non-allosteric Forms of Rat Liver 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase: Differential Inhibition of Activity by Adenosine 2'-monophospho-5'-diphosphoribose"
  • 4. Bailey J. M.Colman F., Biochemistry, 24, 5367 - 5377 (1985), "Affinity Labeling of NADP+-Specific Isocitrate Dehydrogenase by a New Fluorescent Nucleotide Analogue 2-[(4-Bromo-2,3-dioxybutyl)thio]-1,N6-ethenoadenosine 2´,5´-Bisphosphate"