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Alternative structural projections:

8-PIP-cAMP

8- Piperidinoadenosine- 3', 5'- cyclic monophosphate ( 8-PIP-cAMP ), sodium salt
Site-selective PKA agonist
Cat. No.: P 002
    
CAS No.: [31357-06-9]
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Product Name Price (net) Qty
Cat. No.: P 002-10
Unit: 10 µmol / ~4.3 mg
$143.00
For other salt forms or metabolites please inquire. Site-selective cyclic AMP analogue with high selectivity for site A of protein kinase A type I and for site B of type II. Acts synergistically together with analogues having opposite site selectivity. Combination with e.g. 2-Cl-8-HA-cAMP (Cat. No. C 071) preferentially activates type I, while e.g. with 6-MBC-cAMP (Cat. No. M 012) selects type II. Increased metabolic stability and membrane permeability compared to cAMP. Detailed technical information and updated references available. Reference: Skalhegg et al., J. Biol. Chem., 267, 15707 - 15714 (1992).
Cat. No. P 002
CAS number [31357-06-9]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₅H₂₀N₆O₆P · Na
Molecular weight [g/mol] 434,3
Modifications 8-cAMP
Target PKA (cAK) Activator
Lipophilicity 2.17
Absorption max [nm] 273
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
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