0 Items - $0.00
Categories
A to Z

8-pCPT-Ade

8- (4- Chlorophenylthio)adenine ( 8-pCPT-Ade )
Potential metabolite of the Epac agonist 8-pCPT-2'-O-Me-cAMP
Cat. No.: C 069
    
CAS No.: [696574-61-5]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: C 069-10
Unit: 10 µmol
$124.00
Potential metabolite of the specific Epac activator 8-pCPT-2’-O-Me-cAMP (Cat. No. C 041). The corresponding nucleoside (Cat. No. C 070) and the 5’-monophosphate (Cat. No. C 078) are available as well. Detailed technical information available. Reference: Laxman et al., Proc. Natl. Acad. Sci. USA, 103, 19194 - 19199 (2006).
Cat. No. C 069
CAS number [696574-61-5]
Purity > 95% HPLC
Storage temperature -20°C / -4°F
Molecular formula C₁₁H₈ClN₅S
Molecular weight [g/mol] 277,7
Absorption max [nm] 285
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16000
  • 1. Enyeart J. A., Liu H.Enyeart J. J., Am. J. Physiol. Endocrinol. Metab., 301, 941 - 954 (2011), "8-Phenylthio-adenines Stimulate the Expression of Steroid Hydroxylases, Cav3.2 Ca2+ Channels, and Cortisol Synthesis by a cAMP-independent Mechanism"
  • 2. Liu H., Enyeart J. J.Enyeart J. A., J. Biol. Chem., 285, 20040 - 20050 (2010), "ACTH Induces CAv3.2. Current and mRNA by cAMP-dependent and cAMP-independent Mechanism"
  • 3. Enyeart J. A.Enyeart J. J., PloS One, 4, 0 - 0 (2009), "Metabolites of an Epac-Selective cAMP Analog Induce Cortisol Synthesis by Adrenocortical Cells through a cAMP-Independent Pathway"
  • 4. Laxman S., Riechers A., Sadilek M., Schwede F.Beavo J. A., PNAS, 103, 19194 - 19199 (2006), "Hydrolysis Products of cAMP Analogs Cause Transformation of Trypanosoma Brucei from Slender to Stumpy-like Forms"