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8-N₃-ADP

8- Azidoadenosine- 5'- O- diphosphate ( 8-N₃-ADP ), sodium salt
ADP analogue with photoaffinity label
Cat. No.: A 044
    
CAS No.: [59432-65-4]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: A 044-05
Unit: 5 µmol / ~2.3 mg
$132.00

For other salt forms please inquire. Useful for photoaffinity labelling of ADP binding proteins. Detailed technical information available. References: Czarnecki et al., Methods Enzymol., 56, 642 - 653 (1979); Potter & Haley, Methods Enzymol., 91, 613 - 633 (1983); Tombline et al. J. Biol. Chem., 279, 31212 - 31220 (2004). Alternative CAS No.: [102185-14-8] (disodium salt). 

 

Vial containing 500 µl of 10 mM aqueous solution of pH 7.6

Cat. No. A 044
CAS number [59432-65-4]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 7.6
Storage temperature -70°C / -94°F
Light-sensitive True
Molecular formula C₁₀H₁₄N₈O₁₀P₂ (free acid)
Molecular weight [g/mol] 468,2 (free acid)
Absorption max [nm] 281
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13000
UV pH value 6
  • 1. Tombline G., Bartholomew L. A., Urbatsch I. L.Senior A. E., J. Biol. Chem., 279, 31212 - 31220 (2004), "Combined Mutation of Catalytic Glutamate Residues in the Two Nucleotide Binding Domains of P-Glycoprotein Generates a Conformation that Binds ATP and ADP Tightly"
  • 2. Cho S.-W.Yoon H.-Y., J. Biol. Chem., 274, 13948 - 13953 (1999), "Photoaffinity Labeling of Brain Glutamate Dehydrogenase Isoproteins with an Azido-ADP"
  • 3. Potter R. L.Haley B. E., Methods Enzymol., 91, 613 - 633 (1983), "Photoaffinity Labeling of Nucleotide Binding Sites with 8-Azidopurine Analogs: Techniques and Applications"
  • 4. Czarnecki J., Geahlen R.Haley B. E., Methods Enzymol., 56, 642 - 653 (1979), "Synthesis and Use of Azido Photoaffinity Analogs of Adenine and Guanine Nucleotides"