Alternative structural projections:
Fluorescent, membrane- permeant cyclic AMP analogue (λexc 352 nm, λem 436 nm). Detailed technical information available. Reference: Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
| Cat. No. | M 016 |
| CAS number | [909782-76-9] |
| Purity | > 98% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Light-sensitive | True |
| Molecular formula | C₂₂H₂₈N₈O₇P · Na |
| Molecular weight [g/mol] | 570.5 |
| Modifications | 8-cAMP |
| Target | PKA (cAK) Activator |
| Excitation max [nm] | 352 |
| Emission max [nm] | 436 |
| Lipophilicity | 2.45 |
| Absorption max [nm] | 261 / 278 |
- 1. Schweinsberg S., Moll D., Burghardt N. C., Hahnefeld C., Schwede F., Zimmermann B., Drewianka S., Werner L., Kleinjung F., Genieser H.-G., Schuchhardt J.Herberg F. W., Proteomics, 8, 1212 - 1220 (2008), "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
- 2. Dao K. K., Teigen K., Kopperud R. K., Hodneland E., Schwede F., Christensen A. E., Martinez A.Doeskeland S. O., J. Biol. Chem., 281, 21500 - 21511 (2006), "Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition"
- 3. Kraemer A., Rehmann H., Cool R. H., Theiss C., de Rooij J., Bos H.Wittinghofer A., J. Mol. Biol., 306, 1167 - 1177 (2001), "Dynamic Interaction of cAMP with the Rap Guanine-nucleotide Exchange Factor Epac1"
